Results 71 to 80 of about 2,883,104 (305)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Applied Sciences, 2021 Non-interactive zero-knowledge (NIZK) proofs for chosen-ciphertext security are generally considered to give an impractical construction. An interesting recent work by Seo, Abdalla, Lee, and Park (Information Sciences, July 2019) proposed an efficient ...
Youngkyung Lee +2 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Strategy implementation - Leveraging people in adaptive strategy [PDF]
, 2023 Strategy is about making fundamental choices on where to play and how to win to realise an organisation’s goals, and to deliver results within the context of those choices. This identifies two elements of the strategy process: Formulation (thinking) and
Peeters, Carine +2 more
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Gong-kuang zidonghua, 2015 Taking explosion-proof electric driving trackless rubber-tyred vehicle as study object, regenerative braking method and braking microstate of permanent magnet brushless DC traction motor driven by three-phase bridge inverter was analyzed, and the ...
WU Ruibing
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
A rewriting point of view on strategies [PDF]
Electronic Proceedings in Theoretical Computer Science, 2013 This paper is an expository contribution reporting on published work. It focusses on an approach followed in the rewriting community to formalize the concept of strategy.
Hélène Kirchner
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Connecticut's transportation strategy [PDF]
, 2007 Cover title.; "In response to Public Act 06-136, the TSB, as of January 2007, revised and adopted Connecticut's transportation strategy"--Publisher's web site (viewed Mar.
core
The relation between monotonicity and strategy-proofness [PDF]
Social Choice and Welfare, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bettina Klaus, Olivier Bochet
openaire +3 more sources