Results 91 to 100 of about 6,714,983 (312)
Nyamira County Debt Management Strategy Paper 2019
, 2018 The 2019 Nyamira County Government Debt Management Strategy is the fifth to be generated by the County Treasury. This is in line with section 123 of the Public Finance Management Act 2012 which stipulates that on or before the 28th February of each ...
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Review of spent nuclear fuel management in different developed countries
Mechanical Engineering JournalSpent nuclear fuel (spent fuel), which is used nuclear fuel that has been exposed to radiation usually produced by nuclear reactors in nuclear power plants, is an inevitable product from the development of nuclear energy.
Lei SHI, Yihan WANG, Na MA, Hongjun LIU
doaj +1 more source
Global Challenges, 2018 Scientifically‐derived insights are often held as requirements for defensible policy choices. Scientific advisory committees (SACs) figure prominently in this landscape, often with the promise of bringing scientific evidence to decision‐makers.
Steven J. Hoffman +4 more
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National Climate Change Response Strategy 2010 [PDF]
, 2010 In response to the challenges and opportunities posed by climate change, Kenya has developed this National Climate Change Response Strategy. The vision of the Strategy is for a prosperous and climate change resilient Kenya.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
IET OptoelectronicsThe authors demonstrate the use of highly temperature insensitive dense wavelength division multiplexing filters combined with optical reflectors and optical time domain reflectometry to uniquely identify specific optical fibres beyond the optical ...
Stephanie R. Bally +3 more
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National Rice Development Strategy 2008-2018 [PDF]
, 2008 This strategy sets the vision, mission, objectives and strategies that Ministry will pursue in ten years with the aim of facilitating growth and development of the rice sub-sector. It will form the basis of which work plans will be formulated at national
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source