Results 121 to 130 of about 178,636 (293)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

ANALISIS QUICK COUNT DENGAN MENGGUNAKAN METODE STRATIFIED RANDOM SAMPLING (STUDI KASUS PEMILU WALIKOTA BANDUNG 2013)

open access: yes, 2014
Quick Count atau perhitungan suara cepat adalah prediksi hasil Pemilu berdasarkan fakta serta mampu mendeteksi dan melaporkan adanya penyimpangan. Dalam melaksanakan quick count digunakan metode sampling tertentu.
Demokrawati, Fiqa Adha
core  

NEAR OPTIMUM MULTIVARIATE STRATIFIED SAMPLING DESIGN WITH RANDOM MEASUREMENT COSTS [PDF]

open access: yes, 2014
Usually in sample surveys information on more than one characteristic are collected and the data obtained are analyzed to get the required estimates for the multivariate population under study.
Ali, Qazi Mazhar; Department of Statistics and Operations Research, Aligarh Muslim University,Aligarh   +2 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The Effectiveness of Simple and Stratified Random Sampling in Broadcast News Content Analysis

open access: yes, 1996
A comparison of simple random, monthly stratified and quarterly/weekly stratified sampling in content analyses of television news used annual “populations” of network newscasts.
Daniel Riffe   +3 more
core   +1 more source

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