Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Minimum variance stratification of a finite population
This paper considers the combined problem of allocation and stratification in order to minimise the variance of the expansion estimator of a total, taking into account that the population is finite.
Hedlin, Dan
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A new Separated Ratio Estimator in the stratified random sampling [PDF]
The aim of this research is to find a new separated ratio estimator in the stratified random sampling ,three other estimators are compared with the new separated ratio estimator , namely : ordinary separated ratio estimator , combined ratio estimator ...
doaj +1 more source
Accuracy assessment, using stratified plurality sampling, of portions of a LANDSAT classification of the Arctic National Wildlife Refuge Coastal Plain [PDF]
An application of a classification accuracy assessment procedure is described for a vegetation and land cover map prepared by digital image processing of LANDSAT multispectral scanner data.
Card, Don H., Strong, Laurence L.
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Sequestration of imaging studies in MIDRC: stratified sampling to balance demographic characteristics of patients in a multi-institutional data commons. [PDF]
Baughan N +8 more
europepmc +1 more source
A methodology for small scale rural land use mapping in semi-arid developing countries using orbital imagery. Part 5: Experimental and operational techniques of mapping land use [PDF]
The author has identified the following significant results. Scope of the preprocessing techniques was restricted to standard material from the EROS Data Center accompanied by some enlarging procedures and the use of the diazo process.
Lock, B. F., Vangenderen, J. L.
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Enhancing Bee Mite Detection with YOLO: The Role of Data Augmentation and Stratified Sampling
Beekeeping is facing a serious crisis due to climate change and diseases such as bee mites (Varroa destructor), which have led to declining populations, collapsing colonies, and reduced beekeeping productivity. Bee mites are small, reddish-brown in color,
Hong-Gu Lee +6 more
doaj +1 more source

