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Stratum corneum evaluation methods: overview
Skin Research and Technology, 2013Background/purposeThe stratum corneum serves as a main barrier for the skin, minimizing water loss and regulating absorption of substances. Because of its surface location, it is readily available for analysis. Consequently, many techniques are amenable to investigating its content and function.
Kaley, Myer, Howard, Maibach
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Studies on stratum corneum metabolism: function, molecular mechanism and influencing factors
Journal of Cosmetic Dermatology, 2022Stratum corneum is located in the outermost layer of the skin and is the most important part of the skin barrier. Stratum corneum mainly contains keratinocytes, lipids, and desmosomes.
Qian Jiao +4 more
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Stratum corneum Lipid Function
Dermatology, 1991The stratum corneum contains a complex mixture of polar and nonpolar lipids in its intercellular spaces. These lipids, present in form of multiple lamellae, have been investigated for their role in providing the epidermal barrier to transcutaneous water loss, the selective barrier from the inside to the outside of the organism and partly the process of
N Y, Schürer, G, Plewig, P M, Elias
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Biopolymers, 1973
AbstractA model for the hydration behavior of human stratum corneum has been developed from measurements on in vitro samples isolated in a manner which minimized tissue treatment and trauma. Water sorption/desorption rate measurements as a function of water activity, temperature, and tissue integrity are reported.
R L, Anderson +3 more
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AbstractA model for the hydration behavior of human stratum corneum has been developed from measurements on in vitro samples isolated in a manner which minimized tissue treatment and trauma. Water sorption/desorption rate measurements as a function of water activity, temperature, and tissue integrity are reported.
R L, Anderson +3 more
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Skin Pharmacology and Physiology, 2004
The importance of the stratum corneum and its barrier function for infants, especially for newborns, is clinically evident. Research regarding the maturation of the stratum corneum in neonates, i.e. when full barrier function is obtained, has produced varying results.
Y.B. Chiou, U. Blume-Peytavi
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The importance of the stratum corneum and its barrier function for infants, especially for newborns, is clinically evident. Research regarding the maturation of the stratum corneum in neonates, i.e. when full barrier function is obtained, has produced varying results.
Y.B. Chiou, U. Blume-Peytavi
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Polymorphism in stratum corneum lipids
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1994Fourier transform infrared spectroscopy (FTIR) was employed to investigate the thermotropic phase behavior of stratum corneum lipid multilamellae. Stratum corneum (SC), the uppermost layer of mammalian skin, is unusual in many respects. It has been demonstrated that the lipids of the stratum corneum provide the primary electrical and transport ...
B, Ongpipattanakul +2 more
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Hydration of the stratum corneum
International Journal of Cosmetic Science, 1986SynopsisTopically applied water, occlusion and topically applied glycerol were used to investigate and characterize some of the changes which occur in the hydrated stratum corneum. The effects of these treatments were monitored using non‐invasive techniques under controlled conditions.The Servomed Evaporimeter was used to determine natural water flux ...
M D, Batt, E, Fairhurst
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The role of proteases in stratum corneum: involvement in stratum corneum desquamation
Archives of Dermatological Research, 1994The effects of protease inhibitors on cell dissociation were studied in vitro in order to examine the involvement of proteases in stratum corneum desquamation. Stratum corneum sheet (peeled from human backs after sunburn) was incubated in a detergent mixture containing 8 mM N,N-dimethyldodecylamine oxide, 2 mM sodium lauryl sulphate and 60 micrograms ...
Y, Suzuki +3 more
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