Results 101 to 110 of about 68,428 (283)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Research on Switching Characteristics of 3 300 V Full SiC MOSFET Power Module
机车电传动, 2020 Depending on the advantages of SiC MOSFET with faster switching and lower on-state losses, the switching characteristics of a 3 300 V full SiC MOSFET device were studied to make better use of the device. Firstly, the switching processes of the SiC device
Kangkang SUN +5 more
doaj
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Design of a Tri-linked Symmetry IGCT Phase Module with Compact Structure
Kongzhi Yu Xinxi Jishu, 2015 It designed a tri-linked structural symmetry IGCT phase module based on NPC three-level circuit with high density and high reliability. Its electrical design, press mounting design and water-cooling design are highly integrated within one unit.
LI Yanyong, HU Jiaxi, SUN Baotao
doaj
Reduction of Stray Inductance in Power Electronic Modules Using Basic Switching Cells
, 2020 -This paper introduces the concepts of two basic switching cells, P-cell and N-cell, along with their implications in power electronic circuits. The basic switching cells exist in almost every power electronic circuit.
Student Member, IEEE Leon M Tolbert +5 more
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
High Frequency Snubber Circuit for SiC MOSFET Module
Kongzhi Yu Xinxi Jishu, 2016 During high frequency switching condition, overvoltage caused by the coupling oscillation between distributed parameters(inductance, capacitor) on Silicon Cabide(SiC) device will easily lead to breakdown damage of devices and the generated ...
LUO Jianbo, FAN Wei, PENG Kai
doaj
, 2012 International audienceWith the emergence of new power semiconductor devices, the switching speeds are increasing. The stray inductance of switching cells must be minimised to limit the over-voltage of power switches like IGBTs, MOSFETs or HEMTs.
Boulahrouz, Salim +3 more
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source