Results 111 to 120 of about 68,428 (283)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Mechanism of gate voltage spike under digital gate control at IGBT switching operations

Power Electronic Devices and Components
This paper reports the mechanism of gate voltage spike in the turn-off operation by a digital gate control. In the previous work, it was clarified that the gate voltage spike Vg_spike was generated by parasitic inductance and a large gate current change ...
Zaiqi Lou, Thatree Mamee, Katsuhiro Hata, Makoto Takamiya, Shin-ichi Nishizawa, Wataru Saito   +5 more
doaj   +1 more source

Eliminating stray radiation inside large area imaging arrays

, 2018
With increasing array size, it is increasingly important to control stray radiation inside the detector chips themselves. We demonstrate this effect with focal plane arrays of absorber coupled Lumped Element microwave Kinetic Inductance Detectors (LEKIDs)
Baryshev, Andrey, Thoen, David J., Murugesan, Vignesh, Bueno, Juan, Llombart, Nuria, Barry, Peter, Ferrari, Lorenza, Gao, Jian-Rong, Yates, Stephen J. C., Yurduseven, Ozan, Baselmans, Jochem J. A., Zmuidzinas, Jonas, Doyle, Simon M., Bisigello, Yurduseven, Goldsmith, Abazajian, Brien   +17 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Mathematical Proof for the Minimized Stray Fields in Transformers Using Auxiliary Windings Based on State Equations for Evaluation of FEM Results

Iranian Journal of Electrical and Electronic Engineering, 2010
Stray magnetic field is one of the main issues in design of transformers, since it causes non-ideal behavior of transformers. One of the techniques is usually adopted to mitigate the unwanted stray magnetic field is the use of auxiliary windings creating
F. Faghihi, H. Heydari
doaj  

Stray

, 2018
After three long years away, a crippled World War II soldier excitedly returns home to his wife, only to discover her life now revolves around a sinister stray ...
Putnam, Katherine, Law, Dean W.
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Stray inductance evaluation of PCB busbar for double pulse test of SiC power modules

International audienceSiC power modules provide fast switching characteristics that trend to increase the power conversion performance and efficiency. However, fast switching produces high di/dt that interacting with stray inductance can lead to hazard ...
Ngo, Minh-Nhut, Izoulet, Antoine, Gutierrez Galeano, Alonso, Gavelle, Mathieu   +3 more
core  

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source