Results 211 to 220 of about 58,986 (277)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Insulation failure mapping on power transformer bushing using FRA and electrostatic simulation. [PDF]

PLoS One
Al-Ameri SM, Hamanah WM, Salem AA, Yousof MF, Ahmed Al-Gailani S, Abu-Siada A.   +5 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

GaN HEMT Oscillators with Buffers. [PDF]

Micromachines (Basel)
Jang SL, Huang CY, Yang TC, Lu CT.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

A 0.049 mm² 0.5-to-5.8 GHz LNA Achieving a Flat High Gain Based on an Active Inductor and Low Capacitive ESD Protection. [PDF]

Micromachines (Basel)
Dong D, Li Z, Quan Y, He X, Zhang J, Li C, Yu L.   +6 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Superconducting nanowire single-photon detectors for enhanced biomedical imaging. [PDF]

J Biomed Opt
Hughes ECV, Upadhya A, Dholakia K.
europepmc   +1 more source

Maximum torque per flux strategy for induction machines. [PDF]

Sci Rep
Morawiec M, Wogi L.
europepmc   +1 more source

Measurement System for Current Transformer Calibration from 50 Hz to 150 kHz Using a Wideband Power Analyzer. [PDF]

Sensors (Basel)
Rom M, van den Brom HE, Houtzager E, van Leeuwen R, van der Born D, Rietveld G, Muñoz F.   +6 more
europepmc   +1 more source