Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
1 200 V Hybrid SiC Power Module with Low Stray Inductance
In order to realize low stray inductance package of 1 200 V hybrid Silicon Carbide (SiC) power module, the measures were taken including selecting optimum chips, optimizing chip layout and replacing bridge joint with low inductance busbar, so that the ...
LI Chengzhan +4 more
doaj
Loss and decoherence due to stray infrared light in superconducting quantum circuits
We find that stray infrared light from the 4 K stage in a cryostat can cause significant loss in superconducting resonators and qubits. For devices shielded in only a metal box, we measured resonators with quality factors Q = 10^5 and qubits with energy ...
Barends, R. +16 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
First self‐resonant frequency of power inductors based on approximated corrected stray capacitances
Inductive devices are extensively employed in power electronic systems due to their magnetic energy storage and power transfer capabilities. The current trend is towards increasing the frequency of operation in order to reduce the size of the magnetic ...
Ignacio Lope +2 more
doaj +1 more source
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Comparative Study on Application of Hybrid SiC IGBT Device and Si IGBT Device in Rail Transit
Hybrid SiC IGBT uses SiC Schottky diode to replace the anti-parallel diode in traditional IGBT devices, which can reduce the diode reverse recovery loss and IGBT turn-on loss.
Wei TIAN +6 more
doaj
Suppression of common-mode voltage in a PWM rectifier/inverter system [PDF]
This paper proposes a PWM rectifier/inverter system capable of suppressing not only supply harmonic currents but also electromagnetic interference (EMI).
Akagi, Hirofumi, Ogasawara, Satoshi
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

