Results 71 to 80 of about 68,428 (283)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

An Extension of Stray Voltage Capture for Hard Switching Fault Detection in Power Electronics with Half-Bridge Structure

open access: yes, 2020
A short circuit detection based on a Stray Voltage Capture (SVC) cannot robustly detect a Hard Switching Fault (HSF) if an additional stray inductance is present in the short circuit path.
van Duivenbode, Jeroen   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Inductance and resistance calculations for isolated conductors

open access: yes, 2005
In this review paper we present various analytical and numerical calculations for computing the high frequency and low frequency inductance and resistance of isolated conductors.
Goddard, K.F., Roy, A.A., Sykulski, J.K.
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Construction and analysis of precise circuit model for SWPT considering parasitic capacitance

open access: yesWireless Power Transfer
Due to seawater's high conductivity and dielectric constant, the traditional pure inductance model used in air cannot accurately describe the coil model in seawater wireless power transfer (SWPT).
Shike Yu   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Research on stray inductance extraction method for large-size power capacitor

open access: yes机车电传动
Stray inductance present in the commutation loop of converters significantly impacts power semiconductor devices. However, accurately extracting stray inductance from large-size power capacitors remains challenging.
TAN Yifan   +5 more
doaj  

Nonlinear Power Inductors for Large Current Crest Factors

open access: yesJournal of Engineering, 2013
A practical method is presented: how to adjust the inductance curve of a nonlinear (saturable) inductor with respect to a desired shape. For this purpose, a nonlinear model was developed based on finite element method (FEM).
Alexander Stadler   +2 more
doaj   +1 more source

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