Results 111 to 120 of about 26,366,925 (292)

DMD-Based Anti-Strong-Light Detecting and Imaging System

open access: yesApplied Sciences
Strong light interference severely degrades imaging system performance. This paper presents a novel digital micromirror device (DMD)-based imaging system for robust, strong light suppression and long-distance detection.
Zuo Tang   +7 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Optical design of high performance con-focal microscopy with digital micro-mirror and stray light filters

open access: yes, 2010
[[abstract]]This research proposes a newly developed stray light filter in order to eliminate stray light, which otherwise might severely reduce the performance of the con-focal microscopy presented in this research.
Hung, Chuan-Cheng;Fang, Yi-Chin;Tsai, Cheng-Mu;Lin, Chang-Ching;Yeh, Koung-Ming;Wu, Jia-Hua   +6 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A stray light analysis for SO/PHI-HRT and an updated comparison of the inferred magnetic field with SDO/HMI

open access: yesAstronomy & Astrophysics
Context. The High Resolution Telescope of the Polarimetric and Helioseismic Imager on Solar Orbiter (SO/PHI-HRT) operates in an extreme observational environment, observing the Sun as close as 0.28 au.
Sinjan J.   +8 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Stray

open access: yes, 2018
After three long years away, a crippled World War II soldier excitedly returns home to his wife, only to discover her life now revolves around a sinister stray ...
Putnam, Katherine, Law, Dean W.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Stray-light contamination and spatial deconvolution of slit-spectrograph observations

open access: yes, 2011
Context. Stray light caused by scattering on optical surfaces and in the Earth’s atmosphere degrades the spatial resolution of observations.
C. Beck, D. Fabbian, R. Rezaei
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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