Results 61 to 70 of about 4,019,827 (271)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Design and Analysis of a Moon-Based Earth-Radiation Measurement System

Remote Sensing
This research project envisions using a lunar observation platform to measure the full-wave (0.2~100 μm) and shortwave (0.2~4.3 μm) radiation of the Earth, achieving an accurate estimation of the overall radiation budget of the Earth.
Shuqi Li, Zhitao Luo, Yanfeng Liu, Wei Fang, Yuwei Wang, Ruidong Jia, Duo Wu, Baoqi Song, Xiaolong Yi, Xin Ye   +9 more
doaj   +1 more source

Fiber-based Stray Light Suppression in Spectrometers

, 2017
Stray light is known as strong interference in spectroscopic measurements. With the creation of a novel kind of customized fibers, manufactured by the fiber optics group in Jena, Germany, a general experimental solution to this problem is possible.
Gong, Miaoxin
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spectral stray light effect on high-temperature measurements using a near-infrared multi-wavelength pyrometer

, 2014
The spectral stray light is a major, non-negligible error source affecting spectral intensity measurements for optical instruments. The purpose of this study is to investigate the effects of spectral stray light on high-temperature measurements using a ...
Duan MG, Liu JF, 李腾, Fu TR, Fu, TR (reprint author), Tsinghua Univ, Dept Thermal Engn, Beijing Key Lab Utilizat & Reduct Technol CO2, Key Lab Thermal Sci & Power Engn,Minist Educ, Beijing 100084, Peoples R China.   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Deep-Space Background Low-Light Image Enhancement Method Based on Multi-Image Fusion

Applied Sciences
Existing low-light image enhancement methods often struggle to effectively enhance space targets in deep-space contexts due to the effects of extremely low illumination, stellar stray light, and Earth halos.
Feixiang Han, Qing Liu, Huawei Wang, Zeyue Ren, Feng Zhou, Chanchan Kang   +5 more
doaj   +1 more source