Results 81 to 90 of about 4,019,827 (271)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

System for the measurement of ultra-low stray light levels [PDF]

, 1978
An apparatus is described for measuring the effectiveness of stray light suppression light shields and baffle arrangements used in optical space experiments and large space telescopes.
Fannin, B. B., Griner, D. B., Wyman, C. L., Brealt, R. P., Hunt, G. H., Hawkins, C. A., Hurd, W. A., Shelton, G. B.   +7 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Results from computer program for analyzing scattered light suppression systems for large space telescope [PDF]

, 1974
A computer program was developed which has the ability to analyze the performance of most light suppression systems so as to predict the amount of scattered light which will reach the image plane for various conditions of unwanted light input from the ...
Fannin, B. B., Tifft, W. G.
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Optical Design and Stray Light Analysis of Underwater Spectral Radiometer

Applied Sciences
Underwater spectral detection plays an important role in the study of the underwater environment, ecology, oceanography, and environmental monitoring.
Yisu Zhang, Kai Wang, Wei Yue, Shuangkui Liu, Jieling Yu, Xin Ye   +5 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Super Black Coating on the Commercial Black Anodized Al(6061) by Direct and Scalable CVD–Growth of Carbon Nanofibers

Advanced Materials Interfaces
Using carbon‐based super black coatings on optical devices can achieve superior stray light suppression for applications in astronomy. For the first time, the work presents carbon nanofiber‐based black coating on commercial anodized Al(6061), which ...
Thuy – Kieu Truong, Geun Tak Yuk, Joong Bae Kim, Hongseok Youn, Jinsung Rho   +4 more
doaj   +1 more source

Detection Capability Analysis of Field of View-Gated Optical Imaging System for All-Time Star Sensor

Photonics
The field of view (FOV)-gated optical imaging system can relieve the contradiction between a wide FOV and the effective suppression of sky background radiation, making it particularly suitable for all-time star sensors.
Liang Fang, Hui Zhang, Xin Cheng, Zhenjie Fan, Zhiyuan Liao, Qiang Zhang, Rujin Zhao   +6 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source