Results 51 to 60 of about 7,692,155 (296)

Do the effects of vitamin d supplementation on muscle strength differ according to age? [PDF]

open access: yes, 2018
Introduction: Vitamin D plays an important role in musculoskeletal health and its use improves muscle strength. However, the effect of vitamin D use on muscle strength in women of different ages is yet to be investigated.
Bilgilisoy Filiz, M.   +6 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Low strength is related to diminished ground reaction forces and walking performance in older women [PDF]

open access: yes, 2011
The purpose of this study was to determine how lower-limb strength in older women affected gait speed, supportive forces, spatial, and temporal aspects of walking gait.
Kralian, Rachel J.   +2 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

High strength, medium density molded foam [PDF]

open access: yes, 1972
Toluene diisocyanate-based polyurethane produces molded-to-size foam products.
Fender, J. R.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Vibration fatigue comparative test and life prediction for titanium alloy connection structures

open access: yesHangkong gongcheng jinzhan
A large number of mechanical connection structures in aircraft face vibration fatigue problems,and the evaluation of vibration fatigue performance is the key to determine the service life,safety design and evaluation of the structure.
HE Shi   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Research on Suppression of Vibration Caused by Combustion Pressure Pulsation in Aircraft Engines

open access: yesShock and Vibration
Abnormal high-energy narrowband signals appeared in the aircraft engine test. By analyzing the characteristics of the vibration signals and the pressure pulsation signals in the measurement point data of the engine, it can be speculated that the abnormal
Liang Hong   +5 more
doaj   +1 more source

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