Results 61 to 70 of about 326,175 (263)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Technic Characteristics of the Vehicle Bogie of the Second Phase of Wuhan Rail Transit Line 1
机车电传动, 2011 This paper introduced technic characteristics of vehicle bogie of the second phase of Wuhan rail transit line 1, which included bogie structure, main characteristic and technic parameters.
李涛, 陈喜红, 卜旦霞, 刘晖霞
doaj
Fracture Analysis and Fatigue Strength Calculation of Anchor Bolt Used in Circulating Water Pump in Nuclear Power Plant. [PDF]
Scanning, 2021 Chen Q, Zu S, Che Y, Feng D, Li Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Study on the Strength of Components of Two-Tooth Difference Swing Movable Teeth Transmission
工程科学与技术, 2011 : According to the transmission principle of two-tooth difference swing movable teeth transmission, the force analysis of two-tooth difference swing movable teeth transmission was carried out.
Liang Shang-ming, ZHOU Rong-liang, Fu Bo
doaj
Graphical analysis-based calculation method of concrete strength
AIP AdvancesThis study established a three-dimensional random spherical aggregate model of concrete. Models with various volume contents of coarse aggregate were sliced, and slice areas were statistically analyzed. To study the effects of the coarse aggregate volume
Xiaohui Wang +4 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Calculation of the rotational strengths of mononucleosides [PDF]
Journal of the American Chemical Society, 1971 Teng, Nelson N.H. +2 more
openaire +2 more sources