Results 61 to 70 of about 314,299 (267)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Graphical analysis-based calculation method of concrete strength
AIP AdvancesThis study established a three-dimensional random spherical aggregate model of concrete. Models with various volume contents of coarse aggregate were sliced, and slice areas were statistically analyzed. To study the effects of the coarse aggregate volume
Xiaohui Wang +4 more
doaj +1 more source
A Shear Strength Model for a Subsidence Backfill Body Based on Adhesion Friction Theory
Advances in Civil Engineering, 2020 Proper determination of the shear strength of the backfill body used to fill the subsidence is the basis for subsidence restoration and the stability analysis of materials.
Lei Liu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Fracture Analysis and Fatigue Strength Calculation of Anchor Bolt Used in Circulating Water Pump in Nuclear Power Plant. [PDF]
Scanning, 2021 Chen Q, Zu S, Che Y, Feng D, Li Y.
europepmc +1 more source
Shell-model calculation of strength functions
Physics Letters B, 1980 Abstract We show how shell-model calculations that use the Lanczos method may be extended to provide information about the distribution of the initial vector among the eigenstates of the system, without actually calculating these eigenstates. By choosing the initial state appropriately this allows, for example, the calculation of the distribution of ...
R.R. Whitehead, A. Watt, D. Kelvin
openaire +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Technic Characteristics of the Vehicle Bogie of the Second Phase of Wuhan Rail Transit Line 1
机车电传动, 2011 This paper introduced technic characteristics of vehicle bogie of the second phase of Wuhan rail transit line 1, which included bogie structure, main characteristic and technic parameters.
李涛, 陈喜红, 卜旦霞, 刘晖霞
doaj
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source