Results 61 to 70 of about 1,520,494 (296)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 2002 Forward-backward multiplicity correlations in symmetric collisions are calculated independently of the detailed form of the corresponding multiplicity distribution.
Giovannini, A., Ugoccioni, R.
core +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Hierarchies of multipartite entanglement for continuous-variable states
, 2014 We derive a hierarchy of separability criteria for multi-mode continuous variable systems. They permit to study in a unified way the k-partite entanglement of broad classes of Gaussian and non- Gaussian states.
Levi, Federico +2 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Materiales de Construccion, 2019 Visual strength grading is widely used to estimate mechanical properties of structural timber. National visual grades are allocated to strength classes according to European standard EN1912.
D. F. Llana +3 more
doaj +1 more source
Shear strength properties of wet granular materials
, 2006 We investigate shear strength properties of wet granular materials in the pendular state (i.e. the state where the liquid phase is discontinuous) as a function of water content. Sand and glass beads were wetted and tested in a direct shear cell and under
C. Thornton +13 more
core +2 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Persistence in the Zero-Temperature Dynamics of the Diluted Ising Ferromagnet in Two Dimensions
, 1999 The non-equilibrium dynamics of the strongly diluted random-bond Ising model in two-dimensions (2d) is investigated numerically. The persistence probability, P(t), of spins which do not flip by time t is found to decay to a non-zero, dilution-dependent,
A. J. Bray +11 more
core +2 more sources