Results 51 to 60 of about 230,180 (265)

Evaluation of Flexible Road Pavement Construction State Using Objective Strength Criteria

The Baltic Journal of Road and Bridge Engineering, 2007
This article illustrates that by means of our methodology for evaluation of state of flexible road pavement construction (RPC) it is possible with an adequate precision for practical purposes to measure the remaining resource of pavement construction ...
Saulius Butkevicius, Kazys Petkevicius, Kazys Petkevicius, Ipolitas Zenonas Kamaitis   +3 more
doaj  

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The Strength Criterion for the Tension Estimation of High-Pressure Apparatus Dies

Механика машин, механизмов и материалов, 2012
During the diamond dust synthesis the most stressed parts of a high-pressure apparatus are dies. They are subjects to all-around nonuniform compression. The criterion for strength estimation of such elements is required with the next conditions: the high-
A.I. Dudyak , V.M. Khvasko
doaj  

Bimodal strength criterion and constitutive model for cemented sand and gravel

Yantu gongcheng xuebao
In order to explore the intricate mechanical properties of the cemented sand and gravel (CSG), large-scale triaxial shear tests are conducted on the specimens with varying confining pressures and gel contents.
WU Yingli 1 , REN Honglei 1, 2, GUO Wanli 1
doaj   +1 more source

A Simple Three-Dimensional Failure Criterion for Jointed Rock Masses under True Triaxial Compression

Advances in Civil Engineering, 2021
The joint configuration and the intermediate principal stress have a significant influence on the strength of rock masses in underground engineering. A simple three-dimensional failure criterion is developed in this study to predict the true triaxial ...
Yaohui Gao, Chunsheng Zhang, Zhaofeng Wang, Jun Chen   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Method of strength analysis for doubly-curved stiffened orthotropic shells by various strength theories [PDF]

FME Transactions, 2023
The paper proposes a method of strength analysis for materials of thin-walled shell structures reinforced with stiffeners. The shells under consideration were made of orthotropic materials.
Semenov Alexey A.
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source