Results 61 to 70 of about 3,284,997 (300)

Water saturation induced changer in the indirect (Brazilian) tensile strength and the failure mode of some igneous rock materials [PDF]

, 2020
The present study concentrates on water induced strength reduction and variation of the failure mode in indirect (Brazilian) tension tests of several igneous rock materials under three moisture cases of oven-dry, air-dry and fully saturated states.
Komurlu, Eren, Yasar, Serdar
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Phase Formation, Microstructure, and Mechanical Properties of Ni-Cu Bimetallic Materials Produced by Electron Beam Additive Manufacturing

Metals, 2022
The paper presents the results of applying wire-feed electron beam additive manufacturing technology to produce bimetallic samples of CuCr1 copper alloy and Udimet 500 nickel-based superalloy.
Kseniya Osipovich, Denis Gurianov, Andrey Vorontsov, Evgeny Knyazhev, Alexander Panfilov, Andrey Chumaevskii, Nikolai Savchenko, Sergey Nikonov, Valery Rubtsov, Evgeny Kolubaev   +9 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Formation of a bimetallic Ti–Al material by a wire-feed electron-beam additive manufacturing

Frontier Materials & Technologies, 2023
Currently, there is a request from aerospace and aircraft for the construction materials with sufficiently high mechanical strength, thermal creep, corrosion and oxidation resistance. The conventional alloys used for these purposes are too heavy.
Andrey V. Luchin, Elena G. Astafurova, Sergey V. Astafurov, Kseniya A. Reunova, Elena A. Zagibalova, Eugeny A. Kolubaev   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

SIMULATION OF FRACTURE USING A MESH-DEPENDENT FRACTURE CRITERION IN THE DISCRETE ELEMENT METHOD

Facta Universitatis. Series: Mechanical Engineering, 2018
Recently, Pohrt and Popov have shown that for simulation of adhesive contacts a mesh dependent detachment criterion must be used to obtain the mesh-independent macroscopic behavior of the system.
Andrey Dimaki, Evgeny Shilko, Sergey Psakhie, Valentin Popov   +3 more
doaj   +1 more source

High-temperature tensile tester for ceramics [PDF]

, 1974
Apparatus measures tensile strength of rigid, low-density ceramic materials at temperatures up to 1375 K. Tensile grips mate with tensile specimen and form top and bottom of lightweight furnace.
Smith, M.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source