Results 71 to 80 of about 1,105,444 (258)
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Materiales tipo Fibre Reinforced Polymer (FRP) y Textile Reinforced Mortar (TRM) han sido estudiados, comparados y aplicados para reforzar muros de fábrica de ladrillo.
E. Bernat-Maso, C. Escrig, L. Gil
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Slow deformation fronts: model and features of distribution
Our study aimed at investigating the origin and development of ‘slow’ movements in a solid body/medium under loading and studying the role of such movements in the occurrence of critical states, i.e.
P. V. Makarov +2 more
doaj +1 more source
Photocuring Graphene Oxide Liquid Crystals for High-Strength Structural Materials. [PDF]
Riad KB, Hoa SV, Wood-Adams PM.
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
On the Superplastic Deformation in Vanadium-Alloyed High-Nitrogen Steel
The experimental evidence for the realization of a superplastic behavior with 900% elongation in V-alloyed high-nitrogen austenitic Fe-19Cr-22Mn-1.5V-0.3C-0.6N steel was proposed. Using thermomechanical processing, a misoriented grain/subgrain austenitic
Elena Astafurova +7 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

