Results 61 to 70 of about 3,323,410 (297)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Materials & Design, 2019 The problem of formation of resistant strains of bacteria contributes to the development of the fields related to nanoparticles that can become the alternatives of antibiotics. The composite zinc oxide based nanoparticles produced by electrical explosion
A.S. Lozhkomoev +6 more
doaj +1 more source
Metals, 2022 The paper presents the results of applying wire-feed electron beam additive manufacturing technology to produce bimetallic samples of CuCr1 copper alloy and Udimet 500 nickel-based superalloy.
Kseniya Osipovich +9 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
SIMULATION OF FRACTURE USING A MESH-DEPENDENT FRACTURE CRITERION IN THE DISCRETE ELEMENT METHOD
Facta Universitatis. Series: Mechanical Engineering, 2018 Recently, Pohrt and Popov have shown that for simulation of adhesive contacts a mesh dependent detachment criterion must be used to obtain the mesh-independent macroscopic behavior of the system.
Andrey Dimaki +3 more
doaj +1 more source
Sustainable Concrete for the 21st Century Concept of Strength through Durability [PDF]
, 2008 The world is passing through difficult and troubled times, and we live in a rapidly changing world. The construction industry is facing many challenges – global warming, climate change forces, and the capability to achieve sustainable development and ...
Swamy, R.N.
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Cu/Fe MAGNETIC NANOPARTICLES WITH ANTITUMOR ACTIVITY
Сибирский онкологический журнал, 2018 The use of bimetallic nanoparticles of biocompatible metals with magnetic properties is a new approach to combating cancer cells. Nanoparticles of immiscible Fe/Cu metals, with separated phases at the level of one particle, were synthesized by electric ...
O. V. Bakina +6 more
doaj +1 more source