Results 21 to 30 of about 546,339 (218)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Analysis of kinematic factors influencing performance in the Chinese men’s 4 × 100 m relay team

Scientific Reports
To investigate the key factors influencing performance in the men’s 4 × 100 m relay, this study analyzed the relationship between baton exchange kinematics and relay zone performance.
Zhao Li, Caizheng Yue, Zhen Li, Xicheng Wang, Haokai Xu, Zhongshuo Zhao, Keli Deng   +6 more
doaj   +1 more source

The Impact of Stroboscopic Visual Conditions on the Performance of Elite Curling Athletes

Life
Background: In elite curling, precise time perception, speed control, and accuracy are critical components of performance. Stroboscopic training enhances visual processing speed, reaction time, motor skill control, and cognitive abilities by challenging ...
Tianhe Li, Chiyue Zhang, Xiaoyao Wang, Xinai Zhang, Zhiqiang Wu, Yapu Liang   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Effects of different high-intensity interval training modes of wattbike on anaerobic capacity in Chinese national alpine skiers

Scientific Reports
This study compared two anaerobic high-intensity interval training (HIIT) modes with distinct work–rest structures—repeated sprint training (RST) and speed endurance maintenance training (SEMT)—on anaerobic performance in Chinese national-level alpine ...
Yiheng Zeng, Yike Sun, Junlei Lin, Zhonghe Yang, Chengyu Zhou, Wei Li   +5 more
doaj   +1 more source

Effect of Hypoxic Exercise with Different Oxygen Concentrations on Metabolic Outcomes in Obesity: A Systematic Review and Network Meta-Analysis

Life
Objective: This study aimed to systematically evaluate the effects of hypoxic exercise at different oxygen concentrations on body composition, glucose metabolism, and lipid metabolism in individuals with obesity, and to explore potential optimal oxygen ...
Kai Gao, Shuting Liu, Chengyu Zhou, Diandong Lang, Huaichuan Zhang   +4 more
doaj   +1 more source

Effects of physical activity distribution patterns on basketball skill acquisition and physical exercise self-efficacy among Chinese male university students: a randomised controlled trial [PDF]

PeerJ
Background As an open-skills sport, basketball not only enhances university students’ physical fitness and specialised techniques but also influences their technical learning efficiency and exercise self-efficacy through patterns of physical activity ...
Zhuoxiao Liu, Chengyu Zhou, Zhuo Zeng, Huaibo Yang   +3 more
doaj   +2 more sources

Variability of time series barbell kinematics in elite male weightlifters

Frontiers in Sports and Active Living, 2023
IntroductionBarbell kinematics are an essential aspect of assessing weightlifting performance. This study aimed at analyzing the total variability of time series barbell kinematics during repeated lifts in the snatch and the clean and jerk at submaximal ...
Ingo Sandau, Georg Langen, Nico Nitzsche
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source