Results 101 to 110 of about 2,684,306 (351)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Health information management systems and practices in conflict-affected settings: the case of northwest Syria

Globalization and Health
Background In conflict settings, as it is the case in Syria, it is crucial to enhance health information management to facilitate an effective and sustainable approach to strengthening health systems in such contexts.
Reem Ladadwa, Mahmoud Hariri, Muhammed Mansur Alatras, Yasir Elferruh, Abdulhakim Ramadan, Mahmoud Dowah, Yahya Mohammad Bawaneh, Wassel Aljerk, Preeti Patel, Abdulkarim Ekzayez, Nassim El Achi   +10 more
doaj   +1 more source

Behavior of FRP-Strengthened RC Beams with Large Rectangular Web Openings in Flexure Zones: Experimental and Numerical Study

International Journal of Concrete Structures and Materials, 2018
This paper aims to investigate the behavior of fiber reinforced polymer (FRP) strengthened reinforced concrete (RC) beams containing large rectangular web openings in the flexure zone.
Tarek Almusallam, Yousef Al-Salloum, Hussein Elsanadedy, Abdulhafiz Alshenawy, Rizwan Iqbal   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A landscape analysis of clinical trials and infant clinical trials in Kenya, Ethiopia, and Nigeria

Frontiers in Epidemiology
IntroductionGlobal inequality in clinical research capacity and service delivery can be indicated simply by the proportion of clinical trials that a country or region has registered in clinical trial registry databases.
Patrick Amboka, Daniel Kurui, Marylene Wamukoya, Julius Kirimi Sindi, Marta Vicente-Crespo, Marta Vicente-Crespo   +5 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Strengthening with wood and wood based panels

, 2014
In this paper the use of glued wood based panels, solid timber members and additional glulam lamellae for strengthening and reinforcement of glulam members is being discussed. The content of the paper is practically oriented.
Widmann, Robert (author)
core   +1 more source

Antimicrobial resistance databases: opportunities and challenges for public health

npj Antimicrobials and Resistance
Antimicrobial resistance (AMR) databases enable the identification of AMR determinants from pathogen sequence data and the prediction of resistance profiles, enhancing AMR surveillance and informing a range of public health interventions.
Chad M. Centner, Sabrina Di Gregorio, Silvia Argimón, Alice Brankin, Anna Dean, Daniel Marcano Zamora, Silvia Bertagnolio   +6 more
doaj   +1 more source

Strengthening of Steel Structures with High Modulus Carbon Fiber Reinforced Polymer (CFRP) Materials

, 2005
Transportation departments and the telecommunications industry are currently demanding cost-effective rehabilitation and/or strengthening techniques for steel structures, including bridges and monopole towers.
Schnerch, David
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source