Results 91 to 100 of about 860,869 (316)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Strengthening prompt simplicity

open access: yesThe Journal of Symbolic Logic, 2011
AbstractWe introduce a natural strengthening of prompt simplicity which we call strong promptness, and study its relationship with existing lowness classes. This notion provides a ≤wtt version of superlow cuppability. We show that every strongly prompt c.e. set is superlow cuppable. Unfortunately, strong promptness is not a Turing degree notion, and so
David Diamondstone, Keng Meng Ng
openaire   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The Light Inside: A Reflection on an Art Program, Traumatised Women and Thriving during the 2020 Pandemic

open access: yesSpace and Culture, India, 2022
COVID-19 and the lockdown are not the worst things to have been imposed upon the people with whom I work. In fact, their lives marinated in childhood sexual trauma, abuse, neglect, family violence, severe mental ill health, and/or disability, have ...
Anne Riggs
doaj  

Wacana Constitutional Questions dalam Situs Mahkamah: Konteks e-Deliberative Democracy

open access: yesJurnal Konstitusi, 2016
Pengantar Pertengahan akhir tahun 2010 ini terdapati perkara yang menyita perhatian publik ditingkat nasional seperti putusan dalam perkara permohonan Pengujian Undang-Undang Nomor 16 Tahun 2004 tentang Kejaksaan Republik Indonesia terhadap Undang ...
Anom Surya Putra
doaj   +1 more source

Strategy for Strengthening Farmer Groups by Institutional Strengthening

open access: yesJurnal Ekonomi Pembangunan: Kajian Masalah Ekonomi dan Pembangunan, 2015
Agriculture sector becomes a spotlight because this sector will be full of potential but the welfare of farmers who become the leading actor is not guaranteed and has a poor tendency. The purpose of this study is to formulate strategies to strengthen farmers' groups in order to create the marketing of the agricultural sector that benefit farmers.
Purbayu Budi Santoso, Darwanto Darwanto
openaire   +3 more sources

Administration of the Strengthening Basin Communities Program [PDF]

open access: yes, 2014
This audit assessed the effectiveness of the Department of the Environment’s administration of the Strengthening Basin Communities Program in the Murray–Darling Basin.

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