Results 61 to 70 of about 860,869 (316)

Estimating non-communicable disease treatment costs using probability-based cost estimation

open access: yesGlobal Health Action, 2022
The burden and impact of non-communicable diseases (NCDs) are well documented, accounting for 70% of premature deaths globally. In Sub-Saharan Africa, rising NCDs are estimated to account for 27% of mortality by 2020, a 4% increase from 2005.
Claire R. Botha, Sten H. Vermund
doaj   +1 more source

An evaluation of the Strengthening Families Programme in Co. Kildare [PDF]

open access: yes, 2017
This report presents the results of an evaluation of the Strengthening Families Programme (SFP) in Co. Kildare. The evaluation took place between January – April 2017 to explore the perspectives of families and stakeholders involved in the programme ...
Furlong, Mairéad   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A randomised controlled feasibility study investigating the use of eccentric and concentric strengthening exercises in the treatment of rotator cuff tendinopathy

open access: yes, 2014
Objectives: To conduct a feasibility study to compare concentric and eccentric rotator cuff strengthening exercises for rotator cuff tendinopathy.
Marcus Bateman   +3 more
core   +1 more source

TAS Strengthening in the Philippines: Strengthening the TAS Study in Mindoro Oriental, Philippines

open access: yes, 2022
This study complements other TAS strengthening studies in the Gates OR pipeline and is based on the same protocol. Sites where TAS strengthening projects are being carried out will present excellent opportunities for district level IDA studies because of
Hernandez, Leda   +2 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Health information management systems and practices in conflict-affected settings: the case of northwest Syria

open access: yesGlobalization and Health
Background In conflict settings, as it is the case in Syria, it is crucial to enhance health information management to facilitate an effective and sustainable approach to strengthening health systems in such contexts.
Reem Ladadwa   +10 more
doaj   +1 more source

A Strengthening of Brooks' Theorem

open access: yesJournal of Combinatorial Theory, Series B, 1999
This paper mainly proves the conjecture due to \textit{A. Beutelspacher} and \textit{P.-R. Hering} [Ars Comb. 18, 201-216 (1984; Zbl 0554.05025)]. More precisely, the author proves that for sufficiently large \(\Delta\), any graph with maximum degree at most \(\Delta\) and no cliques of size \(\Delta\) has a \(\Delta-1\) colouring.
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A landscape analysis of clinical trials and infant clinical trials in Kenya, Ethiopia, and Nigeria

open access: yesFrontiers in Epidemiology
IntroductionGlobal inequality in clinical research capacity and service delivery can be indicated simply by the proportion of clinical trials that a country or region has registered in clinical trial registry databases.
Patrick Amboka   +5 more
doaj   +1 more source

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