Results 191 to 200 of about 56,561 (304)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

The role of previous streptococcal infections in adult patients with obsessive-compulsive disorder: a research study. [PDF]

CNS Spectr
Marazziti D, Palermo S, Arone A, Carbone MG, Massa L, Crowther LF, Crivelli NSB, Gurrieri R, Weiss F, Mucci F, Dell'Osso L.   +10 more
europepmc   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Risk of Household Secondary Invasive Group A Streptococcal Infections After a Prophylaxis Policy Change.

JAMA Netw Open
de Gier B, Vlaminckx BJM, van Roon A, Knol MJ, Te Wierik MJM, Notermans DW, de Melker HE, van Sorge NM.   +7 more
europepmc   +1 more source

Group B streptococcal infections in pregnancy and early life. [PDF]

Clin Microbiol Rev
Manuel G, Twentyman J, Noble K, Eastman AJ, Aronoff DM, Seepersaud R, Rajagopal L, Adams Waldorf KM.   +7 more
europepmc   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

Interdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao, Panpan Qiao, Yujing Zeng, Murtaza Sayed, Qin Mi, Juan Zhang, Genxi Li   +6 more
wiley   +1 more source

Role of viral coinfection in post-pandemic invasive Group A streptococcal infections in adults, a nation-wide cohort study (iGASWISS). [PDF]

Eur J Clin Microbiol Infect Dis
Musumeci S, MacPhail A, Weisser Rohacek M, Erba A, Goldenberger D, Lang C, Colin-Benoit E, Leib SL, Sendi P, Chuard C, Erard V, Fournier C, Cobuccio L, Tagini F, Bertelli C, Senn L, Sommerstein R, Blättler G, Vieira Gomes C, Moraz M, Emonet S, Strahm C, Kohler P, Seiffert SN, Herzog K, Vuichard Gysin D, Brugger SD, Nolte O, Egli A, Weller D, Andrianaki AM, Zinkernagel AS, Vu DL, Uribe Caparros A, Laurie G, Gaia N, Lazarevic V, François P, Schrenzel J.   +38 more
europepmc   +1 more source

Clinical outcomes of empirical topical nifuratel or nitrofurantoin in Streptococcus pyogenes vulvovaginitis: A retrospective study

International Journal of Gynecology &Obstetrics, EarlyView.
Marek Stefan, Kristyna Krogh, Jaroslava Zikova, Marta Novackova, Marcela Krutova   +4 more
wiley   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Pandemic mitigations reveal an association between superficial group A streptococcal infections and acute rheumatic fever incidence in Auckland New Zealand. [PDF]

Emerg Microbes Infect
Bennett J, Zhang J, Anderson A, Blakiston M, Baker MG, Webb R, Moreland NJ.   +6 more
europepmc   +1 more source