Results 61 to 70 of about 3,289,203 (397)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]

, 2017
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core   +3 more sources

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Infancy narcolepsy: Streptococcus infection as a causal factor

Sleep Science, 2015
Streptococcal infections are suggested as a risk factor for narcolepsy. This hypothesis is supported by the presence of anti-streptolysin antibodies in 65% of patients with narcolepsy.
Danielle Antunes Lopes, Fernando Morgadinho Santos Coelho, Marcia Pradella-Hallinan, Maria Helena de Araújo Melo, Sergio Tufik   +4 more
doaj   +1 more source

The Prevalence of Antibiotic and Toothpaste Sensitivity Found in Oral Streptococcal Isolates in Healthy Individuals in the Okada Community of Nigeria [PDF]

, 2017
Background: This study aimed to determine the prevalence, antibiotic, and toothpaste sensitivity of oral streptococcal isolates in healthy individuals in the Okada community of Nigeria.
Mitsan, O. (Olley), Okwu, M. U. (Maureen)   +1 more
core  

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Invasive Group A Streptococcal Infection in High School Football Players, New York City, 2003

Emerging Infectious Diseases, 2005
After being notified that 2 high school football teammates were hospitalized with confirmed or suspected invasive group A streptococcal infections, we conducted an investigation of possible spread among other team members. This investigation highlights a
Susan E. Manning, Elsie Lee, Maribeth Bambino, Joel Ackelsberg, Don Weiss, Chiminyan Sathyakumar, John Kornblum, Oxiris Barbot, Dwight Johnson, Edward L. Kaplan, Marcelle Layton   +10 more
doaj   +1 more source

Outcome of patients with streptococcal prosthetic joint infections with special reference to rifampicin combinations

BMC Infectious Diseases, 2016
BackgroundOutcome of patients with streptococcal prosthetic joint infections (PJIs) is not well known.MethodsWe performed a retrospective multicenter cohort study that involved patients with total hip/knee prosthetic joint (THP/TKP) infections due to ...
E. Fiaux, M. Titécat, O. Robineau, J. Lora-Tamayo, Y. El Samad, M. Etienne, N. Frebourg, N. Blondiaux, B. Brunschweiler, F. Dujardin, É. Beltrand, C. Loiez, V. Cattoir, J. Canarelli, C. Hulet, M. Valette, S. Nguyen, F. Caron, H. Migaud, É. Senneville, on behalf of the G4 bone and joint infection study group   +20 more
semanticscholar   +1 more source

Single‐Cell RNA Seq in Sydenham Chorea Shows B Cell HLA‐DR/DQ Upregulation and Plasma Cell Proteasomal Activation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han, Brooke A. Keating, Brian S. Gloss, Xianzhong Lau, Ruwani Dissanayake, Hiroya Nishida, Jessica Hayes, Shrujna Patel, Shekeeb S. Mohammad, Russell C. Dale   +9 more
wiley   +1 more source

RAPID DIAGNOSIS OF STREPTOCOCCAL TONSILLITIS IN EPIDEMIOLOGICAL PRACTICES

Журнал инфектологии, 2018
The aim of the study was to conduct clinical testing of the rapid diagnostic test system «Streptatest» (Dectra Pharm, France) and to evaluate its performance in accordance with its purpose in solving the functional problems of express diagnostics of ...
D. A. Zharkov, A. A. Kuzin, S. A. Svistunov, P. I. Ogarkov, G. G. Marуin, R. V. Nikolaev, I. O. Volуnkov   +6 more
doaj   +1 more source