Results 101 to 110 of about 85,647 (300)

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

open access: yesAdvanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan   +12 more
wiley   +1 more source

Rapid Differentiation between Members of the Anginosus Group and Streptococcus Dysgalactiae Subsp. Equisimilis within Beta-Hemolytic Group C and Group G Streptococci by Pcr

open access: yes, 2008
Based on a pair of primers developed initially for differentiating the anginosus group from other viridans streptococci, the PCR reported here can also differentiate between members of the anginosus group and Streptococcus dysgalactiae subsp. equisimilis
LIU, LIANG-CHUN;TSAI, JUI-CHANG;HSUEH, PO-REN;TENG, LEE-JENE   +1 more
core  

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Effects of a Chlorhexidine Varnish on the Mutans Streptococci and on Dental Caries [PDF]

open access: yes, 1997
The purpose of this study was to determine the effects of a chlorhexidine varnish-sealant on the mutans streptococci and on caries outcome variables, in 113 female school-children 10 to 15 years-old, in Rio de Janeiro, Brazil.
C. Djahjah   +5 more
core   +1 more source

Increase in Pneumococcus Macrolide Resistance, United States

open access: yesEmerging Infectious Diseases, 2009
During year 6 (2005–2006) of the Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin surveillance study, 6,747 Streptococcus pneumoniae isolates were collected at 119 centers.
Stephen G. Jenkins, David J. Farrell
doaj   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

open access: yesAdvanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu   +4 more
wiley   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

open access: yesAdvanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou   +14 more
wiley   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

open access: yesAdvanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion   +10 more
wiley   +1 more source

Genetic basis of the association of resistance genes mef(I) (macrolides) and catQ (chloramphenicol) in streptococci

open access: yesFrontiers in Microbiology, 2015
In streptococci mef(I) and catQ, two relatively uncommon macrolide and chloramphenicol resistance genes, respectively, are typically linked in a genetic module designated IQ module.
Marina eMingoia   +4 more
doaj   +1 more source

A comparison of clinical characteristics between nutritionally variant streptococci (NVS) and viridans streptococci

open access: yes, 2012
Background NVS is a fastidious group of streptococci that can give rise to serious invasive infections in humans. Apart from endocarditis, clinical features of this group of pathogens have not been compared with other more commonly encountered ...
呂志侯, Lui, Leo
core  

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