Results 121 to 130 of about 123,761 (305)
IntroductionHuman and animal skin is colonized by a complex microbial population. An imbalance of these microorganisms is often associated with dermatological diseases.MethodsThe aim of this work was to describe the skin bacterial microbiota composition ...
Lucia Štempelová +4 more
doaj +1 more source
Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi +4 more
wiley +1 more source
Does chewing xylitol gum improve oral health? [PDF]
Popular chewing gum brands such as Orbit and Trident advertise that chewing their gum promotes oral health due to the presence of xylitol. This compound has interested oral health researchers since the 1970 s, but recent advances in research have been ...
Rouse, Thomas
core +2 more sources
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo +13 more
wiley +1 more source
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Analysis of interspecies adherence of oral bacteria using a membrane binding assay coupled with polymerase chain reaction-denaturing gradient gel electrophoresis profiling. [PDF]
Information on co-adherence of different oral bacterial species is important for understanding interspecies interactions within oral microbial community.
He, Xue-song +6 more
core
Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Comparison of five genotypic techniques for identification of optochin-resistant pneumococcus-like isolates [PDF]
Claeys, Geert +7 more
core +2 more sources
STARCH HYDROLYZING STREPTOCOCCI [PDF]
H W, SEELEY, J A, DAIN
openaire +2 more sources
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source

