Results 131 to 140 of about 468,046 (357)
Advanced Science, EarlyView.SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui +15 more
wiley +1 more source
Acute tonsillitis at infectious patients
Журнал инфектологии, 2014 We examined 1824 patients with diphtheria treated in Clinical Infectious Diseases Hospital Botkin (St. Petersburg) in 1993 – 1994, and more than 500 patients referred to the clinic with a diagnosis of «angina».
Y. P. Finogeev +3 more
doaj +1 more source
A Bayesian Multivariate Spatial Point Pattern Model: Application to Oral Microbiome FISH Image Data [PDF]
arXivAdvances in cellular imaging technologies, especially those based on fluorescence in situ hybridization (FISH) now allow detailed visualization of the spatial organization of human or bacterial cells. Quantifying this spatial organization is crucial for understanding the function of multicellular tissues or biofilms, with implications for human health ...
arxiv
Engineered Tissue Models to Decode Host–Microbiota Interactions
Advanced Science, EarlyView.Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio +5 more
wiley +1 more source
STUDIES ON THE IMMUNE RESPONSE OF THE RHEUMATIC SUBJECT AND ITS RELATIONSHIP TO ACTIVITY OF THE RHEUMATIC PROCESS. IV. CHARACTERISTICS OF STRAINS OF HEMOLYTIC STREPTOCOCCUS, EFFECTIVE AND NON-EFFECTIVE IN INITIATING RHEUMATIC ACTIVITY 1 [PDF]
, 1935 Alvin F. Coburn, Ruth Pauli
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Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease
Advanced Science, EarlyView.This study has unveiled significant new insights into the role of MS4A4A in Alzheimer's disease‐related epilepsy, highlighting its impact on microglial phagocytosis, mitochondrial metabolism, and cytoskeleton, and demonstrating its therapeutic potential in epilepsy management.
Meng Jiang +10 more
wiley +1 more source
Advanced Science, EarlyView.CuS‐Au heterostructures were synthesized via ligand‐regulated annular‐epitaxial growth strategy, biotin‐Concanavalin A (ConA) was modified on the CuS‐Au heterostructures for universal bacterial‐labelling, assembled with strip, Streptococcus pneumoniae and Klebsiella pneumoniae can be sensitively recognized by SERS/colorimetric/temperature three‐mode ...
Xiaorui Lin +5 more
wiley +1 more source
Advanced Science, EarlyView.This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong +5 more
wiley +1 more source
Chaining and Unchaining Streptococcus faecalis—a Hypothesis of the Mechanism of Bacterial Cell Separation [PDF]
, 1958 I. Lominski, John Cameron, G Wyllie
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Advanced Science, EarlyView.Polyaspartic acid‐calcium‐lanthanum (PAsp‐Ca‐La) complexes could induce antibacterial remineralization of demineralized dentin and in‐depth occlusion of dentinal tubules (DTs) with lanthanum‐doped hydroxyapatite (La‐HAp) via polyelectrolyte‐cation complexes pre‐precursor (PCCP) process, allowing the release of La3+ in response to acids generated by ...
Ling Zhu +12 more
wiley +1 more source