Results 61 to 70 of about 637,457 (296)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Determination of Certain Immunological and Physicochemical Features of Pneumococcal Surface Protein A (PspA): In-silico Cloning of pspA [PDF]

open access: yesModern Medicine
Objective: Pneumococcal surface protein A (PspA) is present in almost all strains of pneumococci and is highly immunogenic, stimulating the production of antibodies. It has a role in pneumococcal pathogenicity.
Enass Waad AL-HADIDI, Ali Adel DAWOOD
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Streptococcus

open access: yes, 2009
Das Ziel dieser Arbeit war die Analyse der Forschungsergebnisse zu den Streptokokken unter szientometrischen Gesichtspunkten, die in einem Zeitraum von 50 Jahren veröffentlicht worden sind (1957-2006). Dafür wurden die Datenbanken „ISI-Web of Science“ des „Thomson Scientific Institute“ und „PubMed“ der „United States National Library of Medicine“ unter
Mark van der Linden   +4 more
openaire   +2 more sources

Serotypes and antimicrobial resistance of meningeal isolates of Streptococcus pneumonia. Cuba, 2007-2012

open access: yesVacciMonitor, 2014
An observational study was conducted to know the serotypes and antimicrobial susceptibility of isolates of Streptococcus pneumoniae responsible for meningitis in Cuba, where there is no vaccine yet to prevent invasive pneumococcal disease.
Gilda Toraño-Peraza   +5 more
doaj  

Association of Novel Streptococcus sanguinis Virulence Factors With Pathogenesis in a Native Valve Infective Endocarditis Model

open access: yesFrontiers in Microbiology, 2020
Streptococcus sanguinis (S. sanguinis) is an abundant oral commensal which can cause disseminated human infection if it gains access to the bloodstream. The most important among these diseases is infective endocarditis (IE). While virulence phenotypes of
Anthony M. Martini   +9 more
doaj   +1 more source

Studies of bacteriophages induced from Streptococcus cremoris strain R1 : is R1 a double Lysogen? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, New Zealand [PDF]

open access: yes, 1979
Early studies on Streptococcus cremoris strain R₁ suggested that it was polylysogenic. Later, it was reported that its induced lysates contained bacteriophages (phages) of two types which were believed to differ in their morphology, buoyant densities ...
Phua, Sin Hen
core  

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Lung abscess in immunocompromised

open access: yesGalicia Clínica, 2020
We present the case of a 44-year-old man, construction worker, hypertensive, smoker, with rheumatoid arthritis under prednisolone 10mg/day for 10 months. Gingival crevice disease. The patient was referred to the Emergency Department after 5 days of right
Teresa Margarida Dias Moreira   +1 more
doaj   +1 more source

Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting

open access: yesAdvanced Functional Materials, EarlyView.
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar   +4 more
wiley   +1 more source

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