Results 91 to 100 of about 87,100 (226)

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

Synergistic engineering of Casδ nuclease for robust genome editing

Journal of Integrative Plant Biology, EarlyView.
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge, Chenchen Peng, Yang Du, Ying Chen, Zilong Zhao, Meixia Yu, Huairu Feng, Yuyang Xie, Siwei Sun, Shengnan Liu, Beibei Xin, Haiming Zhao, Sen Wu, Chao Bian, Zhijia Yang, Jinsheng Lai, Jian Chen   +16 more
wiley   +1 more source

CRISPR/Cas‐Mediated Gene Editing in Plant Immunity and Its Potential for the Future Development of Fungal, Oomycete, and Bacterial Pathogen‐Resistant Pulse Crops

Plant, Cell &Environment, EarlyView.
ABSTRACT Pulses provide myriad health benefits and are advantageous in an environmental context as a result of their leguminous nature. However, phytopathogenic fungi, oomycetes and bacteria pose a substantial threat to pulse production, at times leading to crop failure.
Stacy D. Singer, Mohammed M. Mukthar, Udaya Subedi, Hari Poudel, Guanqun Chen, Nora Foroud, Syama Chatterton   +6 more
wiley   +1 more source

Antibacterial Activity of Etil Acetate Fraction of Chili Leaf Against Streptococcus Pyogenes and Bioautografy

Jurnal Farmasi Sains dan Praktis, 2019
One of the plant that has antibacterial activity is chili leaf (Capsicum frutescens L.). The purpose of this study was to determine the antibacterial activity of ethyl acetate fraction of chili leaf against Streptococcus pyogenes bacteria and conduct ...
Ade Irawan, Nurkhasanah -, Nanik Sulistyani   +2 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Antibiotic susceptibility of Streptococcus species that cause pharyngitis in children

Diyala Journal of Medicine
Background: Group A Streptococcus (GAS) significantly impacts global health, especially among children aged 5–14 years, causing approximately 288 million episodes of sore throat annually and resulting in around 100,000 disability-adjusted life years ...
Ruqaya Ammar Ammin ,, Hani Hameed Wadi ,, Estabraq Abed Hasan AL-Gburi ,, Anfal Shakir Motib ,, Mohammed Hussein Jaber   +4 more
doaj   +1 more source

Prevalence, Antibiotic Susceptibility Profile and Associated Factors of Group A Streptococcal pharyngitis Among Pediatric Patients with Acute Pharyngitis in Gondar, Northwest Ethiopia

Infection and Drug Resistance, 2023
Molla Tadesse,1 Yohanes Hailu,2 Sirak Biset,3 Getachew Ferede,3 Baye Gelaw3 1Department of Medical Microbiology, Jigjiga University, Jigjiga, Ethiopia; 2Department of Pediatrics and Child Health, School of Medicine, University of Gondar, Gondar, Ethiopia;
Tadesse M, Hailu Y, Biset S, Ferede G, Gelaw B   +4 more
doaj  

Clinical implications of imlifidase interference in antibody screening and transfusion management

Transfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani, Aiko P. J. de Vries, Arjan Albersen   +2 more
wiley   +1 more source

Bacterial screening of platelet donations in England, 2014–2023

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Bacterial contamination of blood components is an ongoing problem in transfusion medicine. We analysed the bacterial screening data of platelets from England, 2014–2023, and compared this with data on reported near‐misses and transfusion‐transmitted infections (TTIs). Materials and Methods Anonymized data on bacterial
Vidushi Chugh, Shannah Secret, Katy Davison, Autumn St John, Peter Simmonds, Susan R. Brailsford, Heli Harvala   +6 more
wiley   +1 more source

Kinetics of cytokine profile in response to Mycobacterium bovis BCG and Streptococcus pyogenes activated cells

Data in Brief, 2016
The infection of epithelial cells is a necessary step for Mycobacterium bovis BCG dissemination, but the mechanism of mycobacterial epithelial interactions is not completely understood.
Vivek Verma, Parveen Kumar, Rakesh Singh Dhanda, Manisha Yadav   +3 more
doaj   +1 more source