Results 171 to 180 of about 91,846 (294)

Exploring the roles of conserved context‐dependent cis‐regulatory elements (cdCREs) in multicellularity, human health and disease

The FEBS Journal, Volume 292, Issue 23, Page 6163-6181, December 2025.
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan, Alexander Rattray, Greg Hutchings, Elizabeth Hay, Chris Murgatroyd, Alasdair MacKenzie   +5 more
wiley   +1 more source

Assessing the impact of a temporary class drug order on ethylphenidate-related infections among people who inject drugs in Lothian, Scotland: an interrupted time–series analysis [PDF]

, 2017
Amsterdam, Bernal, Caulkins, Dahlman, Darke, Dunsmuir, Dunsmuir, Giese, Greenfield, Griffith, Griffiths, Hill, Karila, Kontopantelis, Lafferty, Larney, Levine, Lindsay, Loeffler, Luca-Harari, Manea, McAuley, Parks, Reuter, Ryall, Rácz, Rácz, Smyth, Soussan, Taljaard, Van Hout, Wagner, Wilkins, Wood   +33 more
core   +1 more source

Molecular Characterization of the Group A Streptococcus Virulence‐Regulatory System FasBCAX

Molecular Microbiology, Volume 124, Issue 6, Page 521-537, December 2025.
The Fas system of the group A Streptococcus is comprised of three proteins (FasBCA) and a small regulatory RNA (FasX), and it represses adhesin production while also promoting the production of the spreading factor streptokinase. Here, we analyze the Fas proteins to assess how they positively regulate FasX production.
Sushila Baral, Roshika Roshika, Clay P. Renshaw, Ameya Singh, Ashna Prabhu, Ira Jain, Rebekah Woolsey, David Quilici, Yftah Tal‐Gan, Paul Sumby   +9 more
wiley   +1 more source

Fluoroquinolone Resistance in InvasiveStreptococcus pyogenesIsolates Due to Spontaneous Mutation and Horizontal Gene Transfer

, 2006
Mathias W. Pletz, Lesley McGee, Chris Van Beneden, Susan Petit, Megan Bardsley, Miriam Barlow, Keith P. Klugman   +6 more
openalex   +1 more source

Versatile Applications of CRISPR‐Based Programmable T‐DNA Integration in Plants

Plant Biotechnology Journal, Volume 23, Issue 12, Page 5950-5964, December 2025.
ABSTRACT Agrobacterium‐mediated T‐DNA integration into plant genomes represents a cornerstone for transgenic expression in plant basic research and synthetic biology. However, random T‐DNA integration can disrupt essential endogenous genes or compromise transgene expression, stressing the need for targeted integration strategies.
Xiao‐Xia Lin, Ben‐Qiang Gong, Feng‐Zhu Wang, Jian‐Bo Wan, Xiangyu Xiong, Jian‐Feng Li   +5 more
wiley   +1 more source

Group A streptococcus cell-associated pathogenic proteins as revealed by growth in hyaluronic acid enriched media. [PDF]

, 2007
Ashbaugh, Berge, Burova, Caparon, Carapetis, Chaussee, Collin, Cunningham, Dixon, Dryla, Eng, Ferretti, Fiona M. McDonald, Frithz, Gary W. Black, Gasteiger, Gomi, Graham, Graham, Green, Guyre, Houtman, Husmann, Hynes, Hynes, Hynes, Ian Humphery-Smith, Johansson, Kansal, La Penta, Laurent, Lei, Levin, LiCalsi, Lukomski, Malke, Meng Zhang, Mims, Musser, Na, Nannini, Okada, Pancholi, Pancholi, Pancholi, Podbielski, Raeder, Raeder, Ratnayake-Lecamwasam, Senadheera, Shane S. Sturrock, Simon J. Charnock, Sjobring, Smith, Teng, Terao, Thongboonkerd, Voyich, Wilkins, Wilkins   +59 more
core   +1 more source

Biological Effects of F(ab′)2 Fragments Generated by Imlifidase From Anti‐HLA IgG Antibodies From Transplant Patients

HLA, Volume 106, Issue 6, December 2025.
ABSTRACT Imlifidase cleaves intact IgG molecules, generating F(ab′)2 fragments that still bind to the target antigen but are devoid of the Fc‐dependent effector functions, notably complement activation. Imlifidase (Idefirix) has been conditionally approved for desensitisation to enable kidney transplantation in highly sensitised adult patients.
Magali Devriese, Ilaria Carelli, Lisa Giraldo, Alexis Pin, Noé Groshaeny, Sephora Da Silva, Robert Bockermann, Jean‐Luc Taupin   +7 more
wiley   +1 more source

THE FERMENTATION OF GALACTOSE BY STREPTOCOCCUS PYOGENES [PDF]

Journal of Bacteriology, 1954
R H, STEELE, A G, WHITE, W A, PIERCE
openaire   +2 more sources

Invasive disease due to Streptococcus pyogenes: Changes in incidence and prognostic factors

, 2019
María Carmen Suárez-Arrabal, Luis Alberto Sánchez Cámara, María Luisa Navarro Gómez, Mar Santos, Teresa Hernández‐Sampelayo, Emilia Cercenado Mansilla, Jesús Saavedra‐Lozano   +6 more
openalex   +1 more source

Toxic Shock Syndrome Due to Streptococcus pyogenes: A Case Series. [PDF]

Cureus
Tavares T, Domingos J, Zaruba V, Nobre C, Sousa M.   +4 more
europepmc   +1 more source