Results 31 to 40 of about 172,356 (250)

Two cases analysis of streptococcal toxin shock syndrome and necrotizing fasciitis caused by streptococcus pyogenes

生物医学转化, 2023
Objective To explore the therapeutic method of streptococcal toxin shock syndrome and necrotizing fasciitis caused by streptococcus pyogenes. Methods We retrospectively reviewed 2 cases of streptococcus pyogenes infection, summarize the treatment ...
Liu Xiaofeng, Zheng Yongqiang, Lin Liang, Lin Zhenyu, Zhang Jinshan   +4 more
doaj   +1 more source

Toxic Shock-like Syndrome Associated with Necrotizing Streptococcus Pyogenes Infection [PDF]

, 1989
Two patients with toxic shock-like syndrome are presented. Both patients had necrotizing cellulitis due to Streptococcus pyogenes, and both patients required extensive surgical debridement.
Connolly, Thomas L., Connolly, Thomas J., Lanspa, Eugene F., Pavelka, Donald J.   +3 more
core   +1 more source

The Streptococcus pyogenes vaccine landscape

npj Vaccines, 2023
AbstractRecent efforts have re-invigorated the Streptococcus pyogenes (Group A Streptococcus) vaccine development field, though scientific, regulatory and commercial barriers persist, and the vaccine pipeline remains sparse. There is an ongoing need to accelerate all aspects of development to address the large global burden of disease caused by the ...
Donald R. Walkinshaw, Meghan E. E. Wright, Anne E. Mullin, Jean-Louis Excler, Jerome H. Kim, Andrew C. Steer   +5 more
openaire   +3 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Clinical characteristics of children with septic arthritis caused by different pathogenic bacteria

Pediatric Discovery
Septic arthritis is a serious infectious disease in children. In this study, we retrospectively analyzed the relationship between demographics, laboratory values at presentation, reported symptoms at presentation, joint involvement, and distribution ...
Ziyu Li, Gefang Li, Jun Wu, Bo He, Qun Zhang   +4 more
doaj   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Potentially virulence-related extracellular proteins of Streptococcus equi [PDF]

, 2006
Equine strangles, a disease of the upper respiratory tract caused by the bacterium Streptococcus equi subspecies equi, is one of the most commonly diagnosed and serious diseases in horses. However, the molecular basis of S. equi subsp.
Lannergård, Jonas
core   +1 more source

Streptococcus pyogenes carriage rate, associated factors and antimicrobial susceptibility profiles among urban and rural schoolchildren at Gondar city, Northwest Ethiopia

Scientific Reports
Streptococcus pyogenes remains one of the top ten causes of mortality from infectious diseases. Children in low-income nations have high carrier rates of Streptococcus pyogenes, which can serve as a source of infections, including simple superficial ...
Yalewayker Gashaw, Alem Getaneh, Desie Kasew, Mitkie Tigabie, Baye Gelaw   +4 more
doaj   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

A Superficial Skin Scarification Method in Mice to Mimic Streptococcus pyogenes Skin Infection in Humans

, 2020
Skin infections caused by Streptococcus pyogenes are a significant health concern in the tropics and among Indigenous populations of developed countries.
Manisha Pandey, Good, Michael F, Pandey, Manisha, Michael F. Good   +3 more
core   +1 more source