Results 51 to 60 of about 163,088 (241)
Clinical characteristics of children with septic arthritis caused by different pathogenic bacteria
Pediatric DiscoverySeptic arthritis is a serious infectious disease in children. In this study, we retrospectively analyzed the relationship between demographics, laboratory values at presentation, reported symptoms at presentation, joint involvement, and distribution ...
Ziyu Li +4 more
doaj +1 more source
Advanced Science, EarlyView.An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee +11 more
wiley +1 more source
Scientific ReportsStreptococcus pyogenes remains one of the top ten causes of mortality from infectious diseases. Children in low-income nations have high carrier rates of Streptococcus pyogenes, which can serve as a source of infections, including simple superficial ...
Yalewayker Gashaw +4 more
doaj +1 more source
Engineered Transformer Base Editor with Enhanced Editing Efficiency
Advanced Science, EarlyView.A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
Cloning and expression of the enzymatic region of Streptococcal hyaluronidase [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s): Streptococcus pyogenes produces extracellular hyaluronidase enzyme. This enzyme is directly associated with the spread of the organism during infection.
Nafiseh Al-Sadat Mirjamali +4 more
doaj
Медицинская иммунология, 2014 . The aim of study was to compare the influence of lipopolysaccharide (LPS) component from Gram-negative bacteria (E. coli 055:B5), and a lysate of Gram-positive bacterium (Streptococcus pyogenes, type M1, strain 40/58) upon transendothelial migration ...
E. P. Starikova +4 more
doaj +1 more source
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
, 2008 Streptococcus pneumoniae colonizes the mucin-rich environment of the nasopharynx. As colonization may be the first stage of infection, investigation was carried out as to whether the pneumococcus could utilize mucin as a source of nutrient and whether ...
Manco, Sonia +4 more
core +1 more source
IDENTIFICATION OF A STREPTOCOCCUS PYOGENES SF370 GENE INVOLVED IN PRODUCTION OF C-DI-AMP [PDF]
, 2011 2011-02Here we show that bis(3’–5’) cyclic diadenylic acid (c-di-AMP) and a diadenylate cyclase (DAC) domain protein involved in the biosynthesis of c-di-AMP were identified in Streptococcus pyogenes.
KAMEGAYA, TAICHI +2 more
core +1 more source
Antibacterial Effect of Human Milk against Streptococcus pyogenes: an in vitro Study
Althea Medical Journal, 2019 Background: Streptococcus pyogenes infection is one of the common upper respiratory infections among children. Human milk has antibacterial properties that may play a role against infections.
Novi Vicahyani Utami +2 more
doaj +1 more source