Results 61 to 70 of about 55,479 (273)

Minimizing Off‐Target Effects of CRISPR‐Cas9 With Optimized sgRNA: Evaluation of Efficiency and Specificity in the Tumor Protein 53 (TP53) Region

Biotechnology and Bioengineering, EarlyView.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) – Cas9‐based genome editing has emerged as a widely used tool across various disciplines, ranging from molecular biology to gene therapy. This revolutionary technology, which enables precise gene editing, represents a significant advancement in biotechnology, opening new frontiers for ...
Ali Mertcan Köse, Monia Ranalli, Drenka Trivanovic, Irina Maslovaric   +3 more
wiley   +1 more source

The pneumococcal response to oxidative stress includes a role for Rgg. [PDF]

, 2009
Streptococcus pneumoniae resides in the oxygen-rich environment of the upper respiratory tract, and therefore the ability to survive in the presence of oxygen is an important aspect of its in vivo survival. To investigate how S.
Terra, VS, P. W. Andrew, Hasan Yesilkaya (345723), Hinds, Jason, Vanessa S. Terra (3610202), M. E. Bortoni, Andrew, PW, V. S. Terra, Yesilkaya, H, Bortoni, Magda E, Andrew, Peter W, Bortoni, ME, Hinds, J, Peter W. Andrew (153608), Yesilkaya, Hasan, H. Yesilkaya, J. Hinds, Terra, Vanessa S, J. Hinds (7607714)   +18 more
core   +1 more source

Cross‐protective effect of a multicomponent fusion protein vaccine during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. Objectives To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with Strangvac®, a ...
Romain Paillot, J. Richard Newton, Sonia Gonzalez Medina, Sara Frosth, Lars Frykberg, Margareta Flock, Bengt Guss, Jan‐Ingmar Flock, Andrew S. Waller   +8 more
wiley   +1 more source

Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2 [PDF]

, 2002
In the present study we investigated the role of the fibronectin (FN)- and fibrinogen (FGN)-binding protein (FBPS) in the pathogenesis of Streptococcus suis serotype 2 in piglets. The complete gene encoding FBPS from S.
Dijkstra, J., Smit, H.E., Verhaar, R., Alphen, L., van, Greeff, A., de, Robin Verhaar, Loek van Alphen, Herma Buys, Buys, H., Janny Dijkstra, Hilde E. Smith, Astrid de Greeff   +11 more
core   +1 more source

On Amylolytic strains of Streptococcus pyogenes [PDF]

Journal of General Microbiology, 1954
SUMMARY: Strains of Streptococcus pyogenes belonging to Types 2 and 4 elaborated an amylolytic enzyme which was not usually a product of other serological Types though it was occasionally produced by members of Types 1, 9, 22 and Types related to 4, 5 and 25. Sixty-six % of amylolytic strains were untypable by M precipitin tests.
openaire   +2 more sources

Streptococcus pyogenes as the aetiological agent of Henoch–Schönlein purpura [PDF]

, 2017
Henoch–Schönlein purpura is a systemic disease mainly affecting school age children. It is characterised by leukocytoclastic small-vessel vasculitis with the deposition of IgA-containing immune complexes in cutaneous, gastrointestinal, articular and ...
Agata Wawrzyniak, Wawrzyniak, Agata, Kalicki, Bolesław, Bolesław Kalicki, Kundera, Aleksandra, Aleksandra Jagielak, Mierzejewska, Anna, Anna Mierzejewska, Jagielak, Aleksandra, Aleksandra Kundera   +9 more
core   +1 more source

The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis

Journal of Nobel Medical College, 2021
Background: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes.
Brihaspati Sigdel
doaj   +1 more source

STREPTOCOCCUS PYOGENES AND ANTISTREPTOCOCCIC SERUM. [PDF]

The Lancet, 1896
n ...
openaire   +2 more sources

Streptococcus pyogenes adhesion and colonization [PDF]

FEBS Letters, 2016
Streptococcus pyogenes (group A Streptococcus, GAS) is a human‐adapted pathogen responsible for a wide spectrum of disease. GAS can cause relatively mild illnesses, such as strep throat or impetigo, and less frequent but severe life‐threatening diseases such as necrotizing fasciitis and streptococcal toxic shock syndrome.
Brouwer, Stephan, Barnett, Timothy C., Rivera-Hernandez, Tania, Rohde, Manfred, Walker, Mark J.   +4 more
openaire   +6 more sources

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source