Results 51 to 60 of about 20,651 (305)

Streptococcus suis infection and malignancy in man, Spain [PDF]

, 2015
Streptococcus suis is an emerging zoonotic agent. Human infection is associated with occupational exposure to swine. Affected persons are usually, but not always, healthy (1,2). Immunosuppressive conditions can predispose persons to S.
Ardanuy Tisaire, María Carmen, Ariza Cardenal, Javier, Cámara, Jordi, García Somoza, Dolors, Gómez-Zorrilla Martín, Silvia, Lora-Tamayo Morillo-Velarde, Jaime, Peña Miralles, Carmen   +6 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

PCR detection of haemolysin gene of Streptococcus suis type 2

浙江大学学报. 农业与生命科学版, 2004
A PCR assay for rapid and sensitive detection of haemolysin of Streptococcus suis type 2 was established. The PCR primers based on the haemolysin of S. suis type 2 succeeded in amplifying a 1502 bp PCR product.
MA You-zhi, LI Xiao-liang, FANG Wei-huan
doaj   +1 more source

Clinical resistance and decreased susceptibility in Streptococcus suis isolates from clinically healthy fattening pigs [PDF]

, 2013
Streptococcus suis (S. suis) has often been reported as an important swine pathogen and is considered as a new emerging zoonotic agent. Consequently, it is important to be informed on its susceptibility to antimicrobial agents.
Boyen, Filip, Butaye, Patrick, Callens, Benedicte, Dewulf, Jeroen, Haesebrouck, Freddy, Maes, Dominiek   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

PK-PD Integration Modeling and Cutoff Value of Florfenicol against Streptococcus suis in Pigs

Frontiers in Pharmacology, 2018
The aims of the present study were to establish optimal doses and provide an alternate COPD for florfenicol against Streptococcus suis based on pharmacokinetic-pharmacodynamic integration modeling.
Zhixin Lei, Zhixin Lei, Zhixin Lei, Qianying Liu, Qianying Liu, Shuaike Yang, Shuaike Yang, Bing Yang, Bing Yang, Haseeb Khaliq, Kun Li, Kun Li, Saeed Ahmed, Saeed Ahmed, Abdul Sajid, Abdul Sajid, Bingzhou Zhang, Pin Chen, Pin Chen, Yinsheng Qiu, Jiyue Cao, Jiyue Cao, Qigai He   +22 more
doaj   +1 more source

Phage inducible islands in the gram-positive cocci [PDF]

, 2016
The SaPIs are a cohesive subfamily of extremely common phage-inducible chromosomal islands (PICIs) that reside quiescently at specific att sites in the staphylococcal chromosome and are induced by helper phages to excise and replicate.
A Bolotin, A Chopin, A Ruzin, B Frígols, BA Duerkop, C Ubeda, C Ubeda, C Ubeda, C Ubeda, C Ubeda, CH O'Callaghan, CM Hamilton, D Straume, D Viana, Davida Smyth, E Charpentier, E Maiques, G Ram, G Ram, Geeta Ram, IT Paulsen, J Chen, J Chen, J Chen, J Scott, J Scott, J-P Claverys, JA Lindsay, John Chen, José R Penadés, JR Penadés, M Kanehisa, MA Tormo, MD Ferrer, Miguel Martí, MÁ Tormo-Más, MÁ Tormo-Más, N Carpena, N Quiles-Puchalt, N Quiles-Puchalt, Nuria Quiles-Puchalt, RC Matos, Richard P Novick, Roser Martínez-Rubio, RP Novick, RP Novick, Suzanne Humphrey, SV Nguyen   +47 more
core   +1 more source

Streptococcus suisinfections in birds [PDF]

Avian Pathology, 1994
Four cases of Streptococcus suis infection were diagnosed in psittacine birds and four others in zebrafinches, bullfinches, canaries and a duck. The main clinical and pathological manifestation was septicaemia with multiple sudden deaths in nestlings, young and adults. Other cases were solitary, with evidence for secondary involvement of S. suis.
L A, Devriese, F, Haesebrouck, P, de Herdt, P, Dom, R, Ducatelle, M, Desmidt, S, Messier, R, Higgins   +7 more
openaire   +2 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source