Characterization of the xiamenmycin biosynthesis gene cluster in Streptomyces xiamenensis 318. [PDF]
PLoS ONE, 2014 Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing Streptomyces xiamenensis wild-type strain 318 to ...
Yong Yang +5 more
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Dynamical modelling of secondary metabolism and metabolic switches in Streptomyces xiamenensis 318 [PDF]
Royal Society Open Science, 2019 The production of secondary metabolites, while important for bioengineering purposes, presents a paradox in itself. Though widely existing in plants and bacteria, they have no definite physiological roles.
Xiao-Mei Zhu +9 more
doaj +4 more sources
Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis [PDF]
Marine Drugs, 2012 An anti-fibrotic compound produced by Streptomyces xiamenensis, found in mangrove sediments, was investigated for possible therapeutic effects against fibrosis.
Jun Xu +10 more
doaj +5 more sources
Identification of Two Novel Anti-Fibrotic Benzopyran Compounds Produced by Engineered Strains Derived from Streptomyces xiamenensis M1-94P that Originated from Deep-Sea Sediments [PDF]
Marine Drugs, 2013 The benzopyran compound obtained by cultivating a mangrove-derived strain, Streptomyces xiamenensis strain 318, shows multiple biological effects, including anti-fibrotic and anti-hypertrophic scar properties.
Lei Feng +8 more
doaj +4 more sources
Correction to: ‘Dynamical modelling of secondary metabolism and metabolic switches in Streptomyces xiamenensis 318’ [PDF]
Royal Society Open Science, 2019 Xiao-Mei Zhu +9 more
doaj +3 more sources
In vitro antimicrobial activity and characterization of mangrove isolates of streptomycetes effective against bacteria and fungi of nosocomial origin [PDF]
Brazilian Archives of Biology and Technology, 2014 The study aimed at determining the in vitro antimicrobial activity of alkaliphilic and halotolerant actinomycetes isolated from a mangrove ecosystem and identification of a potent strain.
Arijit Das +3 more
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Genomes of four Streptomyces strains reveal insights into putative new species and pathogenicity of scab-causing organisms [PDF]
BMC Genomics, 2023 Genomes of four Streptomyces isolates, two putative new species (Streptomyces sp. JH14 and Streptomyces sp. JH34) and two non thaxtomin-producing pathogens (Streptomyces sp. JH002 and Streptomyces sp.
Laura Henao +4 more
doaj +2 more sources
A Novel AdpA Homologue Negatively Regulates Morphological Differentiation in Streptomyces xiamenensis 318. [PDF]
Appl Environ Microbiol, 2019 AdpA is a key regulator of secondary metabolism and morphological differentiation inStreptomycesspecies. However, AdpA had not been reported to negatively regulate morphological differentiation. Here, we characterized the regulatory role of AdpASxinStreptomyces xiamenensis318, which has a naturally streamlined genome.
Bu XL, Weng JY, He BB, Xu MJ, Xu J.
europepmc +4 more sources
Deciphering the streamlined genome of Streptomyces xiamenensis 318 as the producer of the anti-fibrotic drug candidate xiamenmycin. [PDF]
Sci Rep, 2016 AbstractStreptomyces xiamenensis 318, a moderate halophile isolated from a mangrove sediment, produces the anti-fibrotic compound xiamenmycin. The whole genome sequence of strain 318 was obtained through long-read single-molecule real-time (SMRT) sequencing, high-throughput Illumina HiSeq and 454 pyrosequencing technologies.
Xu MJ +11 more
europepmc +4 more sources
Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase. [PDF]
Sci Rep, 2017 AbstractPolycyclic tetramate macrolactams (PTMs) were identified as distinct secondary metabolites of the mangrove-derived Streptomyces xiamenensis 318. Together with three known compounds—ikarugamycin (1), capsimycin (2) and capsimycin B (3)—two new compounds, capsimycin C (4) with trans-diols and capsimycin D (5) with trans-configurations at C-13/C ...
Yu HL +10 more
europepmc +4 more sources