Dynamical modelling of secondary metabolism and metabolic switches in Streptomyces xiamenensis 318 [PDF]
The production of secondary metabolites, while important for bioengineering purposes, presents a paradox in itself. Though widely existing in plants and bacteria, they have no definite physiological roles.
Xiao-Mei Zhu +9 more
doaj +5 more sources
Characterization of the xiamenmycin biosynthesis gene cluster in Streptomyces xiamenensis 318. [PDF]
Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing Streptomyces xiamenensis wild-type strain 318 to ...
Yong Yang +5 more
doaj +6 more sources
Correction to: ‘Dynamical modelling of secondary metabolism and metabolic switches in Streptomyces xiamenensis 318’ [PDF]
[This corrects the article DOI: 10.1098/rsos.190418.].
Xiao-Mei Zhu +9 more
doaj +4 more sources
Identification of Two Novel Anti-Fibrotic Benzopyran Compounds Produced by Engineered Strains Derived from Streptomyces xiamenensis M1-94P that Originated from Deep-Sea Sediments [PDF]
The benzopyran compound obtained by cultivating a mangrove-derived strain, Streptomyces xiamenensis strain 318, shows multiple biological effects, including anti-fibrotic and anti-hypertrophic scar properties.
Lei Feng +8 more
doaj +5 more sources
A Novel AdpA Homologue Negatively Regulates Morphological Differentiation in Streptomyces xiamenensis 318. [PDF]
AdpA is a key regulator of secondary metabolism and morphological differentiation in Streptomyces species. However, AdpA had not been reported to negatively regulate morphological differentiation.
Bu XL, Weng JY, He BB, Xu MJ, Xu J.
europepmc +5 more sources
Genomes of four Streptomyces strains reveal insights into putative new species and pathogenicity of scab-causing organisms [PDF]
Genomes of four Streptomyces isolates, two putative new species (Streptomyces sp. JH14 and Streptomyces sp. JH34) and two non thaxtomin-producing pathogens (Streptomyces sp. JH002 and Streptomyces sp.
Laura Henao +4 more
doaj +3 more sources
Deciphering the streamlined genome of Streptomyces xiamenensis 318 as the producer of the anti-fibrotic drug candidate xiamenmycin. [PDF]
Streptomyces xiamenensis 318, a moderate halophile isolated from a mangrove sediment, produces the anti-fibrotic compound xiamenmycin. The whole genome sequence of strain 318 was obtained through long-read single-molecule real-time (SMRT) sequencing ...
Xu MJ +11 more
europepmc +5 more sources
Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase. [PDF]
Polycyclic tetramate macrolactams (PTMs) were identified as distinct secondary metabolites of the mangrove-derived Streptomyces xiamenensis 318. Together with three known compounds—ikarugamycin (1), capsimycin (2) and capsimycin B (3)—two new compounds ...
Yu HL +10 more
europepmc +5 more sources
Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis [PDF]
An anti-fibrotic compound produced by Streptomyces xiamenensis, found in mangrove sediments, was investigated for possible therapeutic effects against fibrosis.
Jun Xu +10 more
doaj +5 more sources
Streptomyces xiamenensis sp. nov., isolated from mangrove sediment. [PDF]
Actinomycete strain MCCC 1A01550(T), isolated from the national mangrove reserve in Fujian Province, China, was determined to belong to the genus Streptomyces based on a polyphasic approach. The cell wall of the novel strain contained ll-diaminopimelic acid and galactose.
Jun Xu +5 more
semanticscholar +3 more sources

