Results 31 to 40 of about 539 (126)

Protective effect of some natural products against chemotherapy-induced toxicity in rats

Heliyon, 2019
Aim: There is a great interest in combining anticancer drugs with natural products aiming at maximizing their efficacy while minimizing systemic toxicity.
Heba M.I. Abdallah, Rehab F. Abdel-Rahman, Sally A. El Awdan, Rasha M. Allam, Aliaa E.M.K. El-Mosallamy, Manal S. Selim, Sahar S. Mohamed, Mahmoud S. Arbid, Abdel Razik H. Farrag   +8 more
doaj   +1 more source

Evaluation of Apple Root-Associated Endophytic Streptomyces pulveraceus Strain ES16 by an OSMAC-Assisted Metabolomics Approach [PDF]

, 2021
The One Strain Many Compounds approach (OSMAC) is a powerful and comprehensive method that enables the chemo-diversity evaluation of microorganisms. This is achieved by variations of physicochemical cultivation parameters and by providing biotic and ...
Armin, Reyhaneh, Kusari, Souvik, Mahnkopp-Dirks, Felix, Winkelmann, Traud, Zühlke, Sebastian   +4 more
core   +2 more sources

Endophytic Actinomycetes from Tea Plants (Camellia sinensis): Isolation, Abundance, Antimicrobial, and Plant‐Growth‐Promoting Activities

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Endophytic actinomycetes are a promising source of novel metabolites with diverse biological activities. Tea plants (Camellia sinensis) produce arsenals of phytochemicals, which are linked to a number of medicinal and nutritional properties. However, a systematic investigation into the abundance and diversity of cultivated actinomycetes residing in tea
Wenna Shan, Ying Zhou, Huihui Liu, Xiaomin Yu, Walter Chitarra   +4 more
wiley   +1 more source

Kinetic model of metabolic network for xiamenmycin biosynthetic optimisation

IET Systems Biology, Volume 10, Issue 1, Page 17-22, February 2016., 2016
Xiamenmycins, a series of prenylated benzopyran compounds with anti‐fibrotic bioactivities, were isolated from a mangrove‐derived Streptomyces xiamenensis. To fulfil the requirements of pharmaceutical investigations, a high production of xiamenmycin is needed.
Min‐juan Xu, Yong‐cong Chen, Jun Xu, Ping Ao, Xiao‐mei Zhu   +4 more
wiley   +1 more source

Novel insights into bacterial dimethylsulfoniopropionate catabolism in the East China Sea [PDF]

, 2018
The compatible solute Dimethylsulfoniopropionate (DMSP), made by many marine organisms, is one of Earth’s most abundant organosulfur molecules. Many marine bacteria import DMSP and can degrade it as a source of carbon and/or sulfur via DMSP cleavage or ...
Delei Song, Gui-Peng Yang, Gui-Peng Yang, Heyu Lin, Ji Liu, Ji Liu, Jinchang Liang, Jingli Liu, Jingli Liu, Jonathan D. Todd, Sheng-Hui Zhang, Xiao-Hua Zhang, Xiao-Hua Zhang   +12 more
core   +4 more sources

A Thorough Analysis and Categorization of Bacterial Interrupted Adenylation Domains, Including Previously Unidentified Families [PDF]

, 2020
Interrupted adenylation (A) domains are key to the immense structural diversity seen in the nonribosomal peptide (NRP) class of natural products (NPs). Interrupted A domains are A domains that contain within them the catalytic portion of another domain ...
Garneau-Tsodikova, Sylvie, Lundy, Taylor A., Mori, Shogo   +2 more
core   +2 more sources

Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXRα transcriptional regulation

Natural Product Research, 2018
From the deep sea-derived Streptomyces xiamenensis MCCC 1A01570, eight cyclic dipeptides (1–8) and five phenolics (9–13) were obtained. Cyclo-(I-Pro-D-Leu) (4) could moderately promote the gene transcriptional function of nuclear receptor RXRα, while 2, 3, and 13 showed weak reduction in RXRα gene transcriptional activities induced by 9-cis-retinoid ...
Wei-Xiang, Lin, Chun-Lan, Xie, Mi, Zhou, Man-Li, Xia, Ting-Ting, Zhou, Hai-Feng, Chen, Xian-Wen, Yang, Quan, Yang   +7 more
openaire   +2 more sources

DSYB catalyses the key step of dimethylsulfoniopropionate biosynthesis in many phytoplankton [PDF]

, 2018
Dimethylsulfoniopropionate (DMSP) is a globally important organosulfur molecule and the major precursor for dimethyl sulfide. These compounds are important info-chemicals, key nutrients for marine microorganisms, and are involved in global sulfur cycling,
A Gruber, A Spielmeyer, A Untergasser, AJ Tett, AL Toribio, AMN Caruana, AP Masella, AR Curson, AR Curson, AR Curson, ARJ Curson, ARJ Curson, ARJ Curson, AWB Johnston, BQ Minh, BR Lyon, BT Hovde, C Ku, C Perez-Cruz, C Trossat, CA Heid, D Kumaresan, DH Figurski, DMJ Dickson, F Hillion, G Schwarz, GA Nevitt, GC Yu, HLJ Jones, I Letunic, J Schindelin, J Stefels, J Sun, J Trifinopoulos, JA Berges, JA Downie, JA Fish, JB Raina, JB Raina, JD Todd, JD Todd, JD Todd, JD Todd, JD Todd, JE Beringer, JM Gonzalez, JS Dickschat, K Katoh, K Katoh, KG Porter, KJ Livak, KL Van Alstyne, KR Fixen, LT Nguyen, M Nei, MN Price, NL Bray, NL Kettles, NT Keen, PA Matrai, PJ Keeling, PS Summers, S Baumgarten, S Belviso, S Sunagawa, SA Amin, SF Altschul, SM Sievert, SQ Le, SR Eddy, T Mahmood, T Mock, U Alcolombri, W Sunda   +73 more
core   +4 more sources

Analysis of actinobacterial biodiversity in reservoir sediment and cave soil and screening of isolates for antimycobacterial activity [PDF]

, 2021
A total of 56 presumptive actinobacterial strains was isolated from three different samples taken from the Silvermine Nature Reserve (Table Mountain National Park, Cape Town), namely, cave soil, the wall of the cave and sediment from the shallow waters ...
Rakiep, Adeebah
core   +1 more source

Análisis microbiológico y geoquímico de espeleotemas en cavernas kársticas de la provincia de Napo, Ecuador [PDF]

, 2023
Los microorganismos colonizan y prosperan en la mayoría de ecosistemas a nivel global, incluso aquellos en condiciones extremas como las cavernas. Modificar internamente estos ambientes subterráneos es su función geomicrobiológica principal, porque
Suquillo Morales, Karla Marilyn
core