Protective effect of some natural products against chemotherapy-induced toxicity in rats
Heliyon, 2019 Aim: There is a great interest in combining anticancer drugs with natural products aiming at maximizing their efficacy while minimizing systemic toxicity.
Heba M.I. Abdallah +8 more
doaj +1 more source
Recently Discovered Secondary Metabolites from Streptomyces Species
Molecules, 2022 The Streptomyces genus has been a rich source of bioactive natural products, medicinal chemicals, and novel drug leads for three-quarters of a century. Yet studies suggest that the genus is capable of making some 150,000 more bioactive compounds than all
H. Lacey, P. Rutledge
semanticscholar +1 more source
Determinação de Ácidos Gordos Produzidos por Actinobactérias de Origem Marinha [PDF]
, 2022 Atualmente a investigação está voltada para o ambiente marinho, visto que as condições distintas das terrestres oferecem maior diversidade estrutural e capacidade de produção de metabolitos com atividade biológica única, de grande interesse ...
Cunha, Marlene Brito
core
Streptomyces sp. AN090126 as a Biocontrol Agent against Bacterial and Fungal Plant Diseases
Microorganisms, 2022 Bacteria and fungi are major phytopathogens which substantially affect global agricultural productivity. In the present study, Streptomyces sp. AN090126, isolated from agricultural suppressive soil in Korea, showed broad-spectrum antagonistic activity ...
Khanh Duy Le +5 more
semanticscholar +1 more source
Evaluation of Apple Root-Associated Endophytic Streptomyces pulveraceus Strain ES16 by an OSMAC-Assisted Metabolomics Approach [PDF]
, 2021 The One Strain Many Compounds approach (OSMAC) is a powerful and comprehensive method that enables the chemo-diversity evaluation of microorganisms. This is achieved by variations of physicochemical cultivation parameters and by providing biotic and ...
Armin, Reyhaneh +4 more
core +2 more sources
BioMed Research International, Volume 2018, Issue 1, 2018., 2018 Endophytic actinomycetes are a promising source of novel metabolites with diverse biological activities. Tea plants (Camellia sinensis) produce arsenals of phytochemicals, which are linked to a number of medicinal and nutritional properties. However, a systematic investigation into the abundance and diversity of cultivated actinomycetes residing in tea
Wenna Shan +4 more
wiley +1 more source
Novel insights into bacterial dimethylsulfoniopropionate catabolism in the East China Sea [PDF]
, 2018 The compatible solute Dimethylsulfoniopropionate (DMSP), made by many marine organisms, is one of Earth’s most abundant organosulfur molecules. Many marine bacteria import DMSP and can degrade it as a source of carbon and/or sulfur via DMSP cleavage or ...
Delei Song +12 more
core +4 more sources
A Thorough Analysis and Categorization of Bacterial Interrupted Adenylation Domains, Including Previously Unidentified Families [PDF]
, 2020 Interrupted adenylation (A) domains are key to the immense structural diversity seen in the nonribosomal peptide (NRP) class of natural products (NPs). Interrupted A domains are A domains that contain within them the catalytic portion of another domain ...
Garneau-Tsodikova, Sylvie +2 more
core +2 more sources
DSYB catalyses the key step of dimethylsulfoniopropionate biosynthesis in many phytoplankton [PDF]
, 2018 Dimethylsulfoniopropionate (DMSP) is a globally important organosulfur molecule and the major precursor for dimethyl sulfide. These compounds are important info-chemicals, key nutrients for marine microorganisms, and are involved in global sulfur cycling,
A Gruber +73 more
core +4 more sources
Recent Advances in Silent Gene Cluster Activation in Streptomyces
Frontiers in Bioengineering and Biotechnology, 2021 Natural products (NPs) are critical sources of drug molecules for decades. About two-thirds of natural antibiotics are produced by Streptomyces. Streptomyces have a large number of secondary metabolite biosynthetic gene clusters (SM-BGCs) that may encode
Zhenyu Liu +3 more
semanticscholar +1 more source