Orbital: The Electronic Journal of Chemistry, 2018 The quantification of pharmaceuticals drugs is typically accomplished using chromatography, which requires several pretreatment steps of the sample, demanding time and supplies.
Luciane Miranda +2 more
doaj +3 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Вестник войск РХБ защиты, 2023 In the domestic literature, the industrial production of penicillin and streptomycin is commonly attributed to the representatives of civil institutions and enterprises.
S. N. Chigrinov +4 more
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Advanced Biomedical Research, 2017 Background: Molecular methods for the detection of drug-resistant tuberculosis (DR-TB) are potentially more rapid than conventional culture-based drug susceptibility testing, facilitating the commencement of appropriate treatment for patients with DR-TB.
Sediqe Karimi +5 more
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Correlation between streptomycin intermediate-level resistance and gidB mutation in an endemic multidrugresistant tuberculosis cluster [PDF]
, 2013 Development of streptomycin-resistance in Mycobacterium tuberculosis is usually associated with mutations in rpsL and rrs genes, although up to 50% of clinical streptomycin-resistant isolates may present no mutation in either of these genes.
Couto, Isabel +7 more
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Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N -Diethyl-Substituted AmidoMoieties [PDF]
, 2012 Sulfonamide drugs which have brought about an antibiotic revolution in medicine are associated with a wide range of biological activities.
Ajani, Olayinka O. +4 more
core +5 more sources
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Effects of therapeutants and temperature on pollen germination, pollen tube growth and fruit set in fruit crops : a thesis presented in partial fulfilment of the requirements for the degree of Master of Horticultural Science at Massey University [PDF]
, 1980 This study involved assessments of therapeutant effects on pollination and fruit set; of temperature effects on pollen germination and pollen tube growth in apples, peaches and kiwifruits; of flowerage effects on pollen germination and pollen tube growth
Manandhar, Dwarika Narayan
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Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives [PDF]
, 2010 A simple and efficient method has been developed for the synthesis of various 2-quinoxalinone-3-hydrazone derivatives using microwave irradiation technique. The series of 2-quinoxalinone-3-hydrazone derivatives synthesized, were structurally confirmed by
Ajani, Olayinka O.
core +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source