Results 51 to 60 of about 737,951 (291)
PharmaceuticalsBackground/Objectives: Liposomes are promising carriers for enhancing antibiotic delivery, but their stability under various stress conditions is crucial for clinical applicability.
Luísa Morato Ribeiro +2 more
doaj +1 more source
Frontiers in Microbiology, 2017 We determined the in vitro susceptibility of four aminoglycosides, which are not of the 4,6-disubstituted deoxystreptamine (DOS) subclass against a collection of carbapenem-resistant Enterobacteriaceae (CRE). CRE clinical strains (n = 134) were collected
Ya Hu +11 more
doaj +1 more source
Chemical Assay of Streptomycin B (Mannosido – Streptomycin) [PDF]
Nature, 1948 MORRIS1 has recently described the use of new reagent (0·2 per cent anthrone, a reduction product of anthroquinone, in 95 per cent sulphuric acid) for quantitative determination of carbohydrates. We have found that it can be used not only for distinguishing streptomycin B (a mannoside) from streptomycin A, but also for estimating the amount of the ...
W B, EMERY, A D, WALKER
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Тонкие химические технологииObjectives. To optimize indirect antibody immobilization on gold nanoparticles (GNPs) using anti-species antibodies for enhanced conjugate stability and to develop an immunochromatographic assay (ICA) for antibiotic detection in milk.Methods.
I. V. Maksin +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Streptomycin production from chitin using streptomyces griseus.
, 2004 The production of streptomycin using Streptomyces griseus using two types of chitin as a substrate was studied using a variety of fermentation techniques. Commercial chitin was obtained (Sigma) and comprised chemically purified crab shell.
Richard J.L. Meanwell (7127693)
core +6 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
INVESTIGATING THE EFFECT OF SOME ELICITORS ON BROWN ROT DISEASE AND TUBER YIELD OF POTATO (Solanum tuberosum L.) [PDF]
Journal of Productivity and Development, 2016 Brown rot of potato is a worldwide disease that causes huge agricultural and economical losses. Using synthetic chemicals like antimicrobial pesticide may have adverse effects on consumers and on the environment. The recent trend of control plant disease
Abd el badiee Ezzat, zeyad Moussa
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source