Results 41 to 50 of about 701,343 (258)
Objectives. To optimize indirect antibody immobilization on gold nanoparticles (GNPs) using anti-species antibodies for enhanced conjugate stability and to develop an immunochromatographic assay (ICA) for antibiotic detection in milk.Methods.
I. V. Maksin +7 more
doaj +1 more source
Effects of Temperature on Resistance to Streptomycin in Xanthomonas arboricola pv. pruni [PDF]
Xanthomonas arboricola pv. pruni (Xap) causes the shot hole disease of stone fruits and almonds. This bacterium is a damaging, widespread pathogen distributed across the major stone fruit producing regions of the world.
Ji Ho Song, Hyun Gi Kong
doaj +1 more source
Chemical Assay of Streptomycin B (Mannosido – Streptomycin) [PDF]
MORRIS1 has recently described the use of new reagent (0·2 per cent anthrone, a reduction product of anthroquinone, in 95 per cent sulphuric acid) for quantitative determination of carbohydrates. We have found that it can be used not only for distinguishing streptomycin B (a mannoside) from streptomycin A, but also for estimating the amount of the ...
W B, EMERY, A D, WALKER
openaire +2 more sources
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
We determined the in vitro susceptibility of four aminoglycosides, which are not of the 4,6-disubstituted deoxystreptamine (DOS) subclass against a collection of carbapenem-resistant Enterobacteriaceae (CRE). CRE clinical strains (n = 134) were collected
Ya Hu +11 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
INVESTIGATING THE EFFECT OF SOME ELICITORS ON BROWN ROT DISEASE AND TUBER YIELD OF POTATO (Solanum tuberosum L.) [PDF]
Brown rot of potato is a worldwide disease that causes huge agricultural and economical losses. Using synthetic chemicals like antimicrobial pesticide may have adverse effects on consumers and on the environment. The recent trend of control plant disease
Abd el badiee Ezzat, zeyad Moussa
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

