Results 101 to 110 of about 8,779 (217)
Currently, glucagon-like peptide-1 receptor agonists (GLP-1RAs) are considered promising drugs for the treatment of Alzheimer's disease (AD) and other neurodegenerative diseases due to their complex mechanism of action, which includes (in addition to ...
A. K. Pavlova +7 more
doaj +1 more source
Anti-diabetic effects of Amygdalus lycioides spach in streptozocin-induced diabetic rats [PDF]
Diabetes mellitus is a group of metabolic disorders characterized by elevated blood sugar and abnormalities in insulin secretion and action. There are many anti-diabetic plants, which might supply useful sources for developing new medicines that can be ...
Arshadi,, S. S. +4 more
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Streptozocin and o,p'DDD in the treatment of adrenocortical cancer patients : long-term survival in its adjuvant use [PDF]
BACKGROUND:To evaluate the efficacy of streptozocin and o.p'DDD (SO) in adrenocortical cancer (ACC) patients since other chemotherapeutic regimens have limited effects.PATIENTS AND METHODS:We performed a phase II study with SO therapy in 40 ACC patients (
Eriksson, Barbro, +8 more
core
Background: Diabetes mellitus is a prevalent metabolic disorder. Insulin and oral hypoglycemic drugs are the basis of diabetes therapy. Nevertheless they have important side effects and are not always satisfactory in maintaining euglycemia and avoiding ...
S Kianbakht, H Fallah Huseini
doaj
MORPHOLOGICAL OBSERVATIONS ON PANCREATIC-ISLET BLOOD-VESSELS IN LOW-DOSE STREPTOZOCIN-TREATED MICE [PDF]
The aim of this study was to observe modifications occurring within the blood vessels of pancreatic islets in low-dose streptozocin (STZ)-treated mice.
CHIEFFI, Gabriella +2 more
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Hypoglycemic effect of Satureja montanum L. hydroethanolic extract on diabetic rats [PDF]
ntroduction: Diabetes is one of the most prevalent metabolic disorders which is associated withseveral complications in different organs. Nowadays, medicinal herbs are being widely used totreat diseases. This study was conducted to study the hypoglycemic
Mirazi Naser +2 more
doaj
Immunomodulation of low dose streptozocin diabetes in mice reveals that insulitis is not obligatory for B cell destruction [PDF]
Twenty male C57B16/J mice were injected with 50 μl complete Freund's adjuvant (CFA) 1 wk before and 1 wk after induction of diabetes with 45 mg streptozocin (STZ)/kg body weight i.p. over 5 d. CFA administration prevented islet infiltration. Inflammatory
CHIEFFI, Gabriella +2 more
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Pancreatic duct infiltration in the low-dose streptozocin-treated mouse [PDF]
The pancreatic-duct system was observed during the initial stage of type 1 diabetes in C57BLI6J mice rendered diabetic with low doses of streptozocin.
Linn, T., Papaccio, G., Strate, C.
core
The streptozocin model of diabetes induces neuropathic pain, anhedonia and impaired burrowing in rats [PDF]
Many diabetic patients experience chronic neuropathic pain leading to a reduced quality of life which poses a huge economic burden to the health system and society.
Lione, Lisa
core
Background. Diabetic keratopathy (DK) poses a significant challenge in diabetes mellitus, yet its molecular pathways and effective treatments remain elusive. The aim of our research was to explore the pyroptosis-related genes in the corneal epithelium of
Yi Cui +7 more
doaj +1 more source

