Searching for Mechanisms of Analgesic Activity in the Group of 1<i>H</i>-Pyrrolo[3,4-<i>c</i>]pyridine-1,3(2<i>H</i>)-dione Derivatives-In Vitro and In Vivo Studies. [PDF]
Dziubina A +5 more
europepmc +1 more source
Peptide‐Based Composite Hydrogels Loaded With Chlorogenic Acid for Diabetic Wound Healing
Chronic diabetic wounds are difficult to heal due to persistent inflammation, infection, and impaired angiogenesis. To address this challenge, this study developed an injectable N‐FF/HA composite hydrogel loaded with chlorogenic acid (CGA). This hydrogel enables sustained drug release and exhibits both antibacterial activity and angiogenic properties ...
Siqi Lin +11 more
wiley +1 more source
<i>Psychrobacillus syltrankelensis</i> sp. nov., a new species isolated from soil in the North Caucasus, Russia. [PDF]
Romanenko MN +11 more
europepmc +1 more source
Does Gum Arabic Alter Gene Expression? Diabetic and Obesity as Models: A Mini Review
Gum Arabic (GA) modulates obesity‐ and diabetes‐related gene expression, reducing pro‐inflammatory cytokines (IL‐6, TNF‐α, IL‐1β) and increasing IL‐10. GA elevates pAMPK, pACC, and GLP‐1 while decreasing FASN and leptin, indicating improved energy and lipid metabolism. Oxidative stress markers (SOD, GPx, CAT) rise with GA, alongside increased GLUT3 and
Saber Y. Adam +4 more
wiley +1 more source
Impact of Neuroendocrine Neoplasm-Specific Systemic Treatments on Somatostatin Receptors Expression and Function in Neuroendocrine Tumor Cells. [PDF]
Däubler C +11 more
europepmc +1 more source
Chronic inflammation in diabetic foot ulcers elevates MMP activity and suppresses TIMP and growth factor signaling, impairing tissue repair. Phytochemicals modulate NF‐κB/MAPK pathways and enhance Nrf2–TIMP expression, restoring MMP/TIMP balance, promoting collagen deposition, angiogenesis, and re‐epithelialization, leading to effective wound healing ...
Vishnu Priyan Elaiyaraja +3 more
wiley +1 more source
Sex differences in arterial stiffness in a rat model of type 1 diabetes. [PDF]
Rastogi S +5 more
europepmc +1 more source
Combination therapy with bone marrow-derived mesenchymal stem cell transplantation and propolis improves streptozotocin-induced kidney injury in diabetic rats. [PDF]
Salami F +7 more
europepmc +1 more source
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto +7 more
wiley +1 more source
Impact of neuroendocrine neoplasm-specific systemic treatments on expression and function of CXCR4 in neuroendocrine tumor cells. [PDF]
Däubler C +9 more
europepmc +1 more source

