Results 201 to 210 of about 181,208 (343)

Cardiomyocyte‐Derived USP20 Attenuates Diabetic Cardiomyopathy by Facilitating the Degradation of STING and Mitigating STING‐Mediated Inflammation

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
USP20 directly binds to STING and promotes the degradation of STING through the autophagy pathway by deubiquitinating p62 via its active site C154, thereby alleviating myocardial inflammation and improving ventricular remodeling and heart failure induced by diabetes. ABSTRACT Although extensive clinical and basic research has been conducted on diabetic
Yixin Zhou, Miaomiao Ying, Baozhen Qi, Yunxuan Chen, Weihong Lin, Chunwu Zhang, Jiahui Lin, Yucong Zhang, Zexin Yang, Ziyi Huang, Jun Wu, Xueli Cai, Weijian Huang, Zhouqing Huang, Zhenfeng Cheng, Shanshan Dai   +15 more
wiley   +1 more source

Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice

Brain Research, 2016
W. Oliveira, A. Nunes, M. R. França, L. A. Santos, D. Lós, S. W. Rocha, K. Barbosa, Gabriel Barros Rodrigues, C. Peixoto   +8 more
semanticscholar   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez   +7 more
wiley   +1 more source

Protective effects of alpinumisoflavone against streptozotocin-induced gestational diabetes mellitus in female rats: mechanistic insights and therapeutic potential. [PDF]

Acta Cir Bras
Zhu Y, Zhang Y, Liu F, Xiao J.
europepmc   +1 more source

A Wearable, Dual Closed‐loop Insulin Delivery System for Precision Diabetes Management

Advanced Materials, Volume 38, Issue 8, 6 February 2026.
A wearable dual closed‐loop drug delivery system for diabetes management is presented, featuring an adaptive, on‐body trained edge AI algorithm for precise insulin delivery, which enhances therapeutic accuracy from 92.10% to 98.82%. Abstract Effective blood glucose management is an increasing demand worldwide.
Xuecheng He, Wei Huang, Wensheng Lin, Binbin Cui, Xinyu Tian, Jing Bai, Dingyao Liu, Ivo Pang, Hao Huang, Shixian Lin, Jixiang Zhu, Jinqiang Wang, Shiming Zhang   +12 more
wiley   +1 more source

Resveratrol Analogs Ameliorate Mitochondrial Impairment and Insulin Resistance in a Streptozotocin-Induced In Vitro Model of Alzheimer's Disease. [PDF]

Int J Mol Sci
Paszternák A, Varga K, Gyöngyössy R, Tarnóczi K, Sikur N, Szökő É, Tábi T.   +6 more
europepmc   +1 more source

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

Advanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava, Lydia Herrmann, Eden Ozkan, Abhiram Kunamneni, Vinamra Swaroop, Geetika Nehra, Rohit Srivastava, Pratima Tripathi, Ken Inoki, Julie E. Goodwin   +9 more
wiley   +1 more source

Retraction notice to "Beneficial effect of <i>Caesalpinia pulcherrima</i> linn., on diabetic <i>neuropathy,</i> cognitive dysfunction and cardiac complications in streptozotocin-induced diabetic rats" [Heliyon 10 (2024) e39774]. [PDF]

Heliyon
AnandaKumar SR, Veerapur VP, Roopesh M, Ambika MV, Babitha S, Thippeswamy BS.   +5 more
europepmc   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

Glucose and insulin responses following streptozotocin administration for the induction of a type 1 diabetes mellitus model in Microminipig. [PDF]

J Vet Med Sci
Izumi M, Hano K, Kato T, Hirata A, Thaw P, Seki A, Tanaka M, Ochi K, Suganami T, Kitagawa H, Takasu M.   +10 more
europepmc   +1 more source