Results 111 to 120 of about 2,002,532 (306)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Biophysical and biochemical constraints imposed by salt stress:Learning from halophyte

Frontiers in Plant Science, 2014
Soil salinization is one of the most important factors impacting plant productivity. About 3.6 billion of the world’s 5.2 billion ha of agricultural dryland have already suffered erosion, degradation and salinization.
Bernardo eDuarte, Noomene eSleimi, Isabel eCaçador   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Plant Responses and Tolerance to Salt Stress: Physiological and Molecular Interventions. [PDF]

Int J Mol Sci, 2022
Hasanuzzaman M, Fujita M.
europepmc   +1 more source

Intact Physiological Response to Arousal with Impaired Emotional Recognition in Alexithymia [PDF]

, 2001
Background: The purpose of the present study was to clarify the relationship between the recognition of emotion and physiological response to emotion (i.e. arousal) in alexithymia.
Nielson, Kristy A., Stone, Linda Ann
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Analysis of Acute Stress Reactivity and Recovery in Autonomic Nervous System Considering Individual Characteristics of Stress Using HRV and EDA

IEEE Access
Stress is a complex factor that simultaneously triggers psychological and physiological changes in humans. However, research on the relationship between stress’s psychological and physiological aspects has been limited.
Jinhak Lee, Ho Bin Hwang, Seungjae Lee, Jayon Kim, Jeyeon Lee, Sanghag Kim, Jung Hee Ha, Yoojin Jang, Sejin Hwang, Hoon-Ki Park, Jongshill Lee, In Young Kim   +11 more
doaj   +1 more source

Drought as a Form of Abiotic Stress and Physiological Markers of Drought Stress [PDF]

Journal of Stress Physiology & Biochemistry, 2018
Drought is one of the most common forms of abiotic stress and has direct impact on the viability and productivity of plants. From the point of view of physical chemistry, drought is characterized by a decrease of the water potential of the environment ...
J.S. Shumilina, A.V. Kuznetsova, A.A. Frolov, T.V. Grishina   +3 more
doaj  

Cardiotachometer with linear beat-to-beat frequency response [PDF]

, 1967
Cardiotachometer detects and displays the human heart rate during physiological studies. It provides linear response to the heart rate, records heart rate during rest and under heavy stress, provides a beat-to-beat indication of changes in heart rate ...
Deboo, G. J., Pope, J. M., Smith, D. B. D.   +2 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source