Results 91 to 100 of about 985,739 (265)

Alpha Lipoic Acid as a Protective Mediator for Regulating the Defensive Responses of Wheat Plants against Sodic Alkaline Stress: Physiological, Biochemical and Molecular Aspects. [PDF]

open access: yesPlants (Basel), 2022
Ramadan KMA   +9 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Lumpfish physiological response to chronic stress

open access: yesFrontiers in Marine Science
In this study, we explored the effects of chronic stress on lumpfish (Cyclopterus lumpus) physiological, immune response, health, and plasma free amino acids. 3 groups of lumpfish were exposed to 1-minute air exposure.
Tiago da Santa Lopes   +11 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Impact of Teleworking on Work‐Related and Home‐Related Stress at During the First Global Lockdown–The International COVISTRESS Study

open access: yesBrain and Behavior
Background The initial lockdown during the pandemic of COVID‐19 led to adjustments in working conditions, including extensive use of telecommuting whenever possible, putatively influencing both work‐related and home‐related stress. Objectives Our aim was
Sébastien Couarraze   +18 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Exploring Physiological and Nonphysiological Responses of Sun-Induced Chlorophyll Fluorescence to Different Levels of Water Stress in Winter Wheat

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Sun-induced chlorophyll fluorescence (SIF) has recently been used for the early detection of plant stress. The response of SIF to water stress is complicated by the combination of physiological and nonphysiological dynamics in SIF variations and has not ...
Jingyu Lin, Litao Zhou, Jianjun Wu
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Investigation of the relationship between university students’ attentional impulsivity levels and psychological and physiological stress responses

open access: yesArchives of Medical Science
Introduction The purpose of this study is to investigate the relationship between attentional impulsivity levels and physiological and psychological stress responses of university students.
Burcu Köksal
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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