The impact of sugar-sweetened beverage intake on rat cardiac function
Heliyon, 2019 Aims: Although there is evidence linking sugar-sweetened beverage (SSB) intake with the development of cardio-metabolic diseases, the underlying mechanisms remain unclear.
Natasha Driescher +10 more
doaj +1 more source
Proposed new signal for real-time stress monitoring: Combination of physiological measures [PDF]
AUT Journal of Electrical Engineering, 2017 Human stress is a physiological tension that appears when a person responds to mental, emotional, or physical chal-lenges. Detecting human stress and developing methods to manage it, has become an important issue nowadays.
M. Saidi, H. Hassanpoor, A. Azizi Lari
doaj +1 more source
Cytoprotective functions of amyloid precursor protein family members in stress signaling and aging [PDF]
, 2013 Poster presentation: Molecular Neurodegeneration: Basic biology and disease pathways Cannes, France. 10-12 September 2013. Background: The amyloid precursor protein (APP) is processed via two different metabolic pathways: the amyloidogenic and the non ...
Chang, Steffi +4 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Nose Heat: Exploring Stress-induced Nasal Thermal Variability through Mobile Thermal Imaging
, 2019 Automatically monitoring and quantifying stress-induced thermal dynamic information in real-world settings is an extremely important but challenging problem.
Bianchi-Berthouze, Nadia +4 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
PENGARUH STRES KERJA TERHADAP PRESTASI KERJA PADA KARYAWAN BAGIAN PRODUKSI PERUSAHAAN HOSANA MALANG [PDF]
, 2009 This research is intended to determine the level work stress level and work accomplishment level of HOSANA company malang workers and also to determine whether work stress level comprised of physiological, psychological, and behavior stress have ...
Yusuf Effendi, Hadiyanto
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Physiological characterization of drought stress response and expression of two transcription factors and two LEA genes in three Prunus genotypes [PDF]
, 2016 Global warming has led to a progressive decrease in rainfall, which is reflected by a reduction of water resources in the soil and a negative effect on crop production in Mediterranean areas.
Bielsa Pérez, Beatriz +2 more
core +1 more source