Results 81 to 90 of about 1,096,962 (313)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Physiological monitoring of cardiorespiratory adaptations during rehearsal and performance of contemporary dance. [PDF]
, 2005 Previous research has shown that dance class and rehearsal stress different cardiorespiratory energy systems than dance performance. The aim of the present study was to monitor the physiological parameters of a number of dancers during a 12-week ...
Wyon, Matthew A. +3 more
core +1 more source
Embodied stress: The physiological resonance of psychosocial stress
Psychoneuroendocrinology, 2019 Psychosocial stress is a ubiquitous phenomenon in our society. While acute stress responses are necessary and adaptive, excessive activation of neurobiological stress systems can predispose an individual to far-reaching adverse health outcomes. Living in a complex social environment, experiencing stress is not limited to challenges humans face ...
Veronika Engert +2 more
openaire +4 more sources
Arquivos Brasileiros de Cardiologia, 2012 FUNDAMENTO: O estresse crônico está associado à remodelação cardíaca; entretanto, os mecanismos permanecem a ser descobertos. OBJETIVO: A proposta deste estudo foi testar a hipótese de que o estresse crônico promove disfunção cardíaca associada a ...
Thiago Bruder-Nascimento +6 more
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Role of stress in progression of Migraine
International Journal of Endorsing Health Science Research, 2014 The mental and physiological stresses can be an important trigger of migraines & headaches. These strains act to enhance the progression of migraine that could be psychological, physiological stress, Environmental stress or Chemical stress.
Shamoon Noushad +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular and physiological study of water-deficit stress on selected Eragrostis species
, 2002 Bibliography: leaves 60-73.Eragrostis nindensis and Eragrostis tef are wild and domestic grasses respectively that belong to the subfamily Eragrostideae. E. nindensis is desiccation tolerant while E. tef is desiccation sensitive.
Ginbot, Zekarias Gebremedhin
core
Physiological response of glutamine and glutamic acid supplemented broiler chickens to heat stress [PDF]
, 2015 This study was conducted to investigate the effects of dietary glutamine (Gln) + glutamic acid (Glu) supplementation on growth performance and physiological stress response broilers exposed to cyclic heat stress.
Soleimani, Abdoreza Farjam +4 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source