Results 101 to 110 of about 1,096,962 (313)

Personalities in female domesticated pigs: behavioural and physiological indications [PDF]

open access: yes, 2000
The inconclusive evidence so far on the existence of distinct personality types in domesticated pigs, led us to perform the present experiment. A total of 128 gilts from 31 sows were systematically studied from birth to slaughter in two identical trials.
Ruis, Marko A.W.   +23 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Balancing stress and recovery in sports [PDF]

open access: yes, 2010
To reach elite level in sports, athletes have to start their intensive and time-consuming training at an early stage. The road to the top is a stressful one, not only due to the physiological stress of training, but also caused by psychological and ...
Brink, Michel Sanne,   +2 more
core  

Reduction of photosynthetic sensitivity in response to abiotic stress in tomato is mediated by a new generation plant activator [PDF]

open access: yes, 2013
Background: Yield losses as a result of abiotic stress factors present a significant challenge for the future of global food production. While breeding technologies provide potential to combat negative stress-mediated outcomes over time, interventions ...
Pickup, Doug   +7 more
core   +1 more source

EFFECT OF WORKPLACE STRESS ON JOB PERFORMANCE

open access: yesEconomic Review, 2015
The study examines the relationship between workplace stress and job performance. A survey method was employed to gather self-administered questionnaires from executive and non-executive employees of a leading private investment bank in Peninsular ...
Azman Ismail   +4 more
doaj   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Transcriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology [PDF]

open access: yes, 2012
peer-reviewedBackground: Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal ...
David J Lynn   +19 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Teamwork reduces physiological stress in junior surgeons

open access: yes, 2014
Objective: The quality of teamwork depends not only on communication skills but also on team familiarity and hierarchical structures. The aim of the present study is to evaluate the physiological impact of close teamwork between senior and junior ...
Candinas, Daniel   +7 more
core  

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